Selenoproteins synergistically protect porcine skeletal muscle from oxidative damage via relieving mitochondrial dysfunction and endoplasmic reticulum stressOA |
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作者姓名: | Jinzhong Jing Ying He Yan Liu Jiayong Tang Longqiong Wang Gang Jia Guangmang Liu Xiaoling Chen Gang Tian Jingyi Cai Lianqiang Che Bo Kang Hua Zhao |
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作者单位: | 2. College of Animal Science and Technology, Sichuan Agricultural University |
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基金项目: | partially supported by the National Natural Science Foundation of China (No. 31772643 and 31272468); |
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摘 要: | Background The skeletal muscle of pigs is vulnerable to oxidative damage, resulting in growth retardation. Selenoproteins are important components of antioxidant systems for animals, which are generally regulated by dietary selenium(Se) level. Here, we developed the dietary oxidative stress(DOS)-inducing pig model to investigate the protective effects of selenoproteins on DOS-induced skeletal muscle growth retardation.Results Dietary oxidative stress caused porcine skeletal muscle oxidative dama...
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