The dual antimicrobial and immunomodulatory roles of host defense peptides and their applications in animal productionOA |
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作者姓名: | Di Wu Linglong Fu Weizhang Wen Na Dong |
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作者单位: | State Key Laboratory of Animal Nutrition,College of Animal Science and Technology,China Agricultural University |
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基金项目: | funded by NSFC grand (32172754); |
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摘 要: | Host defense peptides(HDPs) are small molecules with broad-spectrum antimicrobial activities against infectious bacteria,viruses,and fungi.Increasing evidence suggests that HDPs can also indirectly protect hosts by modulating their immune responses.Due to these dual roles,HDPs have been considered one of the most promising antibiotic substitutes to improve growth performance,intestinal health,and immunity in farm animals.This review describes the antimicrobial and immunomodulatory roles of host ...
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