| A review of the pangenome: how it affects our understanding of genomic variation,selection and breeding in domestic animals?OA |
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| 作者姓名： | Ying Gong Yefang Li Xuexue Liu Yuehui Ma Lin Jiang |
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| 基金项目： | supported by the National Natural Science Foundation of China (grant numbers 31961143021)；;the earmarked fund for Modern Agro-industry Technology Research System (grant numbers CARS-39-01)；;the Science and Technology Innovation Project of the Chinese Academy of Agricultural Sciences (grant numbers ASTIP-IAS01) to YM and LJ； |
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| 摘 要： | As large-scale genomic studies have progressed, it has been revealed that a single reference genome pattern cannot represent genetic diversity at the species level. While domestic animals tend to have complex routes of origin and migration, suggesting a possible omission of some population-specific sequences in the current reference genome. Conversely, the pangenome is a collection of all DNA sequences of a species that contains sequences shared by all individuals(core genome) and is also able t...
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