The synbiotic mixture of lactulose and Bacillus coagulans protects intestinal barrier dysfunction and apoptosis in weaned piglets challenged with lipopolysaccharideOA |
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作者姓名: | Weijiang Zheng Zuyan Zhao Yunnan Yang Liren Ding Wen Yao |
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作者单位: | 1. College of Animal Science and Technology, Nanjing Agricultural University;2. National Experimental Teaching Center for Animal Science, College of Animal Science and Technology, Nanjing Agricultural University;3. Key Lab of Animal Physiology and Biochemistry, Ministry of Agriculture |
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基金项目: | supported by the National Key R&D Program of China (2017YFE0114400); |
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摘 要: | Background Lactulose as an effective prebiotic protects intestinal mucosal injury. Bacillus coagulans is widely used in feed additives because of its ability to promote intestinal health. Our previous study suggests that the combination of lactulose and Bacillus coagulans may be a good candidate as alternative for antibiotic growth promoters. However,the in vivo effects of lactulose and Bacillus coagulans on growth and intestinal health under immune challenge in piglets remains unclear. The obje...
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