Renal dysplasia in a pig

A diagnosis of renal dysplasia was made in a six-month-old, male, mixed-breed pig. Both kidneys were small, firm, slightly pitted, and contained an indistinct corticomedullary junction. Histologically, primitive tubules were present surrounded by an abundant loose, mesenchymatous stroma. Occasionally, tubules were markedly dilated and lined by a pseudostratified columnar epithelium forming epithelial mats that obscured the lumina. Immature glomeruli were present. Multifocal glomerular sclerosis was evident. Other mature glomeruli were enlarged and characterized by mesangial cell hyperplasia forming an arborizing pattern.