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Differences in natural antibody titres comparing free-ranging guanacos (Lama guanicoe) and capybaras (Hydrochoerus hydrochaeris)
Authors:Andrea L Racca  Ayelen T Eberhardt  Pablo G Moreno  Cecilia Baldi  Pablo M Beldomenico
Institution:1. Department of Veterinary Science and Public Health, University of Milan, Via Celoria 10, 20133 Milan, Italy;2. Veterinary Laboratory, Poggio dei Pini, 09012 Capoterra, Cagliari, Italy;3. Clinical Pathology Unit, Central Laboratory, Veterinary Teaching Hospital, University of Milan, Via dell’Università 6, 26900 Lodi, Italy;1. Normandie Université, UNICAEN, SF 4206 ICORE, Frank Duncombe Laboratory, 1 Route de Rosel, 14053 Caen cedex 4, France;2. Merial S.A.S., 29 Avenue Tony Garnier, 69007 Lyon, France;3. Department of Physiology, Faculty of Veterinary Medicine, University of Liège, 20 Boulevard de Colonster, Bat. B42, 4000 Liège, Belgium;4. Normandie Université, UNICAEN, EA 4655 – U2RM, 14032 Caen, France;1. Department of Veterinary Microbiology, University of Miyazaki, Miyazaki 889-2192, Japan;2. Department of Veterinary Pathology, University of Tokyo, Tokyo 113-8657, Japan;3. Division of Infection Control and Disease Prevention, Department of Veterinary Medical Science, University of Tokyo, Tokyo 113-8657, Japan;1. Clinic for Ruminants, Vetsuisse-Faculty, University of Bern, Switzerland;2. Veterinary Public Health Institute, Vetsuisse-Faculty, University of Bern, Switzerland;3. Institute of Agricultural Sciences, Swiss Federal Technical School of Zürich, Switzerland
Abstract:Natural antibodies are an important component of innate humoral immunity but have not been investigated to any great extent in wild mammals. In the current study, serum natural antibody titres were measured by hemagglutination assay for two South American herbivores, the guanaco (Lama guanicoe) and the capybara (Hydrochoerus hydrochaeris). Results indicated that capybaras had antibody titres on average more than four times higher than guanacos (median titres 1:256 and 1:4, respectively), suggesting differences in investment in constitutive humoral immunity between the two species.
Keywords:Eco-immunology  Natural antibodies  Immunological response  Wild mammals
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