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伊维菌素与丙硫咪唑对内蒙古两地区放牧绵羊胃肠道线虫驱杀效果
引用本文:王鹏龙,罗晓平,敖登高娃,刘阳,方变变,李超,王瑞,李军燕,杨晓野.伊维菌素与丙硫咪唑对内蒙古两地区放牧绵羊胃肠道线虫驱杀效果[J].中国农业大学学报,2019,24(11):117-122.
作者姓名:王鹏龙  罗晓平  敖登高娃  刘阳  方变变  李超  王瑞  李军燕  杨晓野
作者单位:内蒙古农业大学 兽医学院, 呼和浩特 010018,内蒙古农业大学 兽医学院, 呼和浩特 010018;内蒙古自治区农牧业科学院 兽医研究所, 呼和浩特 010031,内蒙古农业大学 兽医学院, 呼和浩特 010018,内蒙古农业大学 兽医学院, 呼和浩特 010018,内蒙古农业大学 兽医学院, 呼和浩特 010018,内蒙古自治区兽药监察所, 010010,内蒙古农业大学 兽医学院, 呼和浩特 010018,内蒙古自治区农牧业科学院 兽医研究所, 呼和浩特 010031,内蒙古农业大学 兽医学院, 呼和浩特 010018
基金项目:国家自然科学基金项目(31660710);内蒙古农牧业创新基金项目(CXJJM01)
摘    要:为了解内蒙古地区放牧绵羊胃肠道线虫对常用驱虫药物的耐药情况,选取呼和浩特和林格尔地区和包头萨拉齐地区自然状态下,感染胃肠道线虫的放牧绵羊各60只,随机分为3组,每组20只,其中2个试验组分别采用伊维菌素或丙硫咪唑进行驱虫,对照组则不做处理,采用粪便虫卵减少试验方法,对其驱虫效果进行评估。结果表明:和林格尔地区绵羊胃肠道线虫使用伊维菌素或丙硫咪唑处理72 h后,粪便虫卵减少率分别是28%和77%;萨拉齐地区绵羊粪便虫卵减少率分别是40%和100%。研究发现:两地区放牧绵羊胃肠道线虫对伊维菌素有着较高的耐药性;和林格尔地区绵羊对丙硫咪唑耐药性程度较轻;在萨拉齐地区,丙硫咪唑驱虫效果较好。

关 键 词:绵羊  内蒙古  伊维菌素  丙硫咪唑  胃肠道线虫  耐药性
收稿时间:2019/4/11 0:00:00

Effects of ivermectin and albendazole on the gastrointestinal nematodes of grazing sheep in Inner Mongolia
WANG Penglong,LUO Xiaoping,Aodenggaow,LIU Yang,FANG Bianbian,LI Chao,WANG Rui,LI Junyan and YANG Xiaoye.Effects of ivermectin and albendazole on the gastrointestinal nematodes of grazing sheep in Inner Mongolia[J].Journal of China Agricultural University,2019,24(11):117-122.
Authors:WANG Penglong  LUO Xiaoping  Aodenggaow  LIU Yang  FANG Bianbian  LI Chao  WANG Rui  LI Junyan and YANG Xiaoye
Institution:College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot 010018, China,College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot 010018, China;Animal Husbandry Institute, Inner Mongolia Academy of Agricultural&Animal Husbandry Sciences, Hohhot 010031, China,College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot 010018, China,College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot 010018, China,College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot 010018, China,Veterinary Drug Control Institute of Inner Mongolia Autonomous Region, Hohhot 010010, China,College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot 010018, China,Animal Husbandry Institute, Inner Mongolia Academy of Agricultural&Animal Husbandry Sciences, Hohhot 010031, China and College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot 010018, China
Abstract:To understand the situation of the resistance in gastroinstestinal nematodes of grazing sheep to current anthelmintics (ivermectin and albendazole),an investigation was carried out by taking 60 grazing sheep infected with gastroinstestinal nematodes in Helinger,Hohhot and Salaqi,Baotou as study objects.The grazing sheep were randomly divided into 3 groups with 20 in each group.Two experimental groups were respectively treated with ivermectin or albendazole,while the control group received no treatment.Faecal egg count reduction tests were employed to determine the efficacy of the these two drugs against gastroinstestinal nematodes infection.The results showed that the reduction in arithmetic mean faecal egg counts achieved by ivermectin or albendazole in Helinger were 28% and 77% after 72 h of treatment,respectively,and their effects were respectively 40% and 100% in Salaqi.This study indicated that there was high resistace of ivermectin against the gastrointestinal nematodes in grazing sheep in two areas and there were mildly resistance of albendazole in Helinger.However,albendazole appeared to be very effective on sheep in Salaqi.
Keywords:sheep  Inner Mongolia  ivermectin  albendazole  gastrointestinal nematodes  drug resistance
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