A systematic review of the effects of injectable sedative and anesthetic drugs and inhalant anesthetics on intraocular pressure in the dog |
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| Institution: | 1. Psychology Department, University of North Georgia, Dahlonega, GA, USA;2. Veterinary Referral Surgical Practice, Roswell, GA, USA;3. Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA, USA;1. Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, USA;2. Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, USA;3. Department of Biological and Diagnostic Services, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, USA;4. Office of Information and Technology, University of Tennessee, Knoxville, TN, USA;5. Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, CA, USA;1. Royal Veterinary College, Department of Veterinary Clinical Sciences, London, UK;2. Universite de Montreal Faculte de medicine, Montreal, QC, Canada;3. Anderson Moores Veterinary Specialists, Winchester, UK;4. Davies Veterinary Specialists, Higham Gobion, Hertfordshire, UK;1. School of Veterinary Medicine, Louisiana State University, USA;2. Department of Clinical Veterinary Medicine, Vetsuisse Faculty, University of Bern, Bern, Switzerland;1. Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, MN, USA;2. Veterinary Medical Center, College of Veterinary Medicine, University of Minnesota, St Paul, MN, USA |
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| Abstract: | ObjectiveThe purpose of this systematic review was to summarize the results of studies that have determined the effect of injectable and inhalant drugs used in anesthesia on intraocular pressure (IOP) in dogs.Databases usedA comprehensive search of research literature was performed without language restriction. The search utilized the PubMed, CAB Abstracts and the University of Georgia’s Galileo electronic databases using a combination of free text terms ‘Ophthalmology’, ‘Intraocular Pressure’, ‘Anesthetic’, ‘Anesthesia’, ‘Canine’ or ‘Dog’. The time frame searched was from 1970 to October 2018. Any published research paper that dealt with sedatives or anesthetics administered systemically and the canine eye was evaluated.ConclusionsThe effects of many anesthetic drugs in dogs with ocular pathology are largely unknown. Many anesthetic drugs do not induce clinically relevant changes in IOP in dogs with normal eyes, although some studies demonstrated results with statistically significant changes. The dose, route of administration, experimental conditions, drug combinations, timing of measurements, measurement technology and setting or individual animal characteristics may all produce some heterogeneity in results from multiple studies. |
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| Keywords: | anesthesia dog intraocular pressure sedation |
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