N-氨甲酰谷氨酸锰的合成工艺研究

为探索NCG-Mn的最佳合成工艺，采用液相合成法，以N-氨甲酰谷氨酸(N-carbamyl-L-glutamate,NCG)和氯化锰为原料，合成了NCG-Mn配合物.通过单因素试验和正交试验研究了NCG与Mn的反应物质的量比、反应液pH值以及反应时间这3种因素对配合物产率的影响.正交试验表明最佳合成工艺条件为：NCG∶Mn反应物质的量比2∶3，反应体系pH 7，反应时间1 h.

Synthesis process of N-carbamyl-L-glutamate manganese

In order to explore the best synthesis process of NCG-Mn complex, as raw material NCG and manganese chloride tetrahydrate were used to synthesize this complex by liqued phase synthesis method. The molar ratio of NCG∶Mn, pH of reaction solution and reaction time were studied through single factor experiment and orthogonal experiment. The optimal reaction conditions were that: the molar ratio of NCG∶Mn was 2∶3; the pH value was 7 and the reaction time was 1 h.