Comparison of bioactive compounds content, free radical scavenging and anti-acne inducing bacteria activities of extracts from the mangosteen fruit rind at two stages of maturity |
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Authors: | Werayut Pothitirat Mullika Traidej Chomnawang Roongtawan Supabphol Wandee Gritsanapan |
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Institution: | aDepartment of Pharmacognosy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand;bDepartment of Microbiology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand;cDepartment of Physiology, Faculty of Medicine, Srinakarintarawirot University, Bangkok, Thailand |
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Abstract: | Contents of bioactive components, free radical scavenging and anti-acne producing bacteria activities of young and mature fruit rind extracts of mangosteen were compared. The young fruit rind extract contained significantly higher contents of phenolics and tannins and promoted higher free radical scavenging activity than the mature fruit rind extract, while the later extract contained higher contents of flavonoids and α-mangostin xanthone and gave higher anti-acne producing bacteria activity than the young fruit rind extract. Thus, the young and mature stages of mangosteen fruit rind should be beneficial for further development of antioxidant and anti-acne pharmaceutical preparations, respectively. |
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Keywords: | Garcinia mangostana Antibacterial activity Antioxidant activity Acne vulgaris Propionibacterium acnes Staphylococcus epidermidis Mangosteen |
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