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Efficiency of Matricaria chamomilla CH12 and number of doses of rabies vaccine on the humoral immune response in cattle
Authors:Luis Souza Lima de Souza Reis   Neuza Maria Frazatti-Gallina   Rosana de Lima Paoli   Rogerio Giuffrida   Avelino Albas   Eunice Oba   Paulo Eduardo Pardo
Abstract:This study evaluated the effect of Matricaria chamomilla and vaccination frequency on cattle immunization against rabies. Four groups (n = 15 /group) were treated with or without Matricaria chamomilla CH12 and vaccinated with one or two doses of rabies vaccine (30 day interval). No effect of chamomile was found on cattle immunization against rabies; however, antibody titers were protective in cattle vaccinated twice, while 93.3% of cattle vaccinated only once had titers under 0.5 UI/ml after 60 days. In conclusion, the use of chamomile did not alter the humoral immune response in cattle, and two vaccine doses are suggested for achieving protective antibody titers.
Keywords:cattle   immune response   Matricaria chamomilla   rabies   vaccine
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