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外源性谷氨酰胺和谷氨酸对早期断奶仔猪肠粘膜形态、结构和小肠吸收功能及骨骼肌中DNA、RNA浓度的影响
引用本文:刘涛,彭健,周诗其,程学慧,陈钢. 外源性谷氨酰胺和谷氨酸对早期断奶仔猪肠粘膜形态、结构和小肠吸收功能及骨骼肌中DNA、RNA浓度的影响[J]. 中国兽医学报, 2003, 23(1): 62-65
作者姓名:刘涛  彭健  周诗其  程学慧  陈钢
作者单位:1. 华中农业大学猪遗传育种农业部重点开放实验室,湖北,武汉,430070
2. 华中农业大学,畜牧兽医学院,湖北,武汉,430070
基金项目:湖北省自然科学基金资助项目 ( 99J10 1)
摘    要:74头28日龄健康二元杂交断奶仔猪分成3组,用于研究外源性谷氨酰胺(glutamine,Gln)和谷氨酰(glutamate, Glu)对断奶仔猪小肠粘膜形态,结构和功能及骨骼肌中DNA,RNA合成的影响。结果表明:与对照组相比,添加1%谷氨酰胺或1%谷氨酸可防止断奶后1周内空肠绒毛萎缩,减少断奶后2周内空肠固有膜内未成熟细胞数;显著改善断奶后1周内小肠吸收功能,并促进肌肉中RNA合成。这些结果为利用Gln、Glu缓解仔猪断奶应激,改善生产性能提供了实验基础。

关 键 词:外源性谷氨酰胺 谷氨酸 早期断奶仔猪 肠粘膜形态 结构 小肠吸收功能 骨骼肌 DNA RNA浓度的影响
文章编号:1005-4545(2003)01-0062-04
修稿时间:2001-06-06

Effects of Glutamine and Glutamate on Small Intestinal Structure, Active Absorption and DNA, RNA Concentrations in Muscle Tissue of Early Weaned Piglets
LIU Tao ,PENG Jian ,ZHOU Shi-qi ,CHENG Xue-hui ,CHEN Gang. Effects of Glutamine and Glutamate on Small Intestinal Structure, Active Absorption and DNA, RNA Concentrations in Muscle Tissue of Early Weaned Piglets[J]. Chinese Journal of Veterinary Science, 2003, 23(1): 62-65
Authors:LIU Tao   PENG Jian   ZHOU Shi-qi   CHENG Xue-hui   CHEN Gang
Affiliation:LIU Tao 1,PENG Jian 1,ZHOU Shi-qi 2,CHENG Xue-hui 1,CHEN Gang 1
Abstract:Seventy-four piglets were used to investigate the effect of exogenous Glutamine and Glutamate on the intestinal feature,struct ure and active absorption and DNA,RNA concentrations of muscle in early-weaned piglets.The results suggested that:compared with control piglets,glutamine and g lutamate supplementation(1%) prevented intestinal atrophy during the first week postweaning and improved the ability to absorb nutrients of small intestine,as w ell as the RNA concentration in muscle tissue.These results provide an experimen tal basis for use of Glutamine and Glutamate on alleviating the weaning stress a nd improving the growth performance.
Keywords:glutamine  glutamate  early-weaned piglets  smal l intestine  muscle
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