Immunologic study of systemic aspergillosis in German shepherd dogs |
| |
| Authors: | M J Day C E Eger S E Shaw W J Penhale |
| |
| Institution: | 1. Division of Veterinary Biology School of Veterinary Studies, Murdoch University, Murdoch, Western Australia, 6150 Australia;2. Division of Applied Veterinary Medicine School of Veterinary Studies, Murdoch University, Murdoch, Western Australia, 6150 Australia |
| |
| Abstract: | Data are presented from a series of eight cases of disseminated canine aspergillosis (A. terreus) in German Shepherd dogs referred to Murdoch University Veterinary Hospital. Immunoglobulin determination revealed depression of serum IgA (cases 1 and 5) and IgM (case 2) levels and elevated levels of IgG in all cases. Total complement activity (CH50) and complement components tests, (C3, C4) were present in normal amounts in all cases. Using agar gel diffusion, serum antibody to A. terreus was found in only one case and aspergillus antigenaemia in two of the remainder. Lectin transformation of lymphocytes in two dogs was found to be depressed relative to normal controls in case 1 and initially in case 2. Two dogs failed to respond to the intradermal injection of A. terreus antigen. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
