| 鹿茸提取物对糖尿病小鼠血糖及衰老的影响 |
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| 引用本文： | 刘瑜,王振宇,周丽萍.鹿茸提取物对糖尿病小鼠血糖及衰老的影响[J].东北林业大学学报,2010,38(5). |
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| 作者姓名： | 刘瑜 王振宇 周丽萍 |
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| 作者单位： | 东北林业大学,哈尔滨,150040;东北林业大学,哈尔滨,150040;东北林业大学,哈尔滨,150040 |
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| 摘 要： | 为了研究鹿茸提取物对四氧嘧啶(ALX)诱导糖尿病小鼠的降糖和抗衰老作用,利用ALX建立了糖尿病小鼠模型,并将鹿茸提取物(RD)分为低(1.6mg/g)、中(3.2mg/g)、高(4.8 mg/g)3个剂量组,对建模成功小鼠连续灌胃4周.试验结果与模型对照组相比,鹿茸提取物能极显著地降低ALX糖尿病小鼠血糖水平、丙二醛(MDA)浓度,提高肝(肌)糖元质量分数以及超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-PX)、麦芽糖酶(CAT)的活性,增强机体抗氧化能力.鹿茸提取物能有效地控制糖尿病小鼠血糖水平,提高机体抗衰老能力.
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| 关 键 词： | 鹿茸提取物 小鼠 糖尿病 血糖 抗衰老 |
Anti-hyperglycemic and Anti-aging Effects of Deer Antler Velvet Extract on Diabetic Mice Induced by Alloxan |
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| Liu Yu,Wang Zhenyu,Zhou Liping.Anti-hyperglycemic and Anti-aging Effects of Deer Antler Velvet Extract on Diabetic Mice Induced by Alloxan[J].Journal of Northeast Forestry University,2010,38(5). |
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| Authors: | Liu Yu Wang Zhenyu Zhou Liping |
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| Institution: | Liu Yu,Wang Zhenyu,Zhou Liping(School of Forestry,Northeast Forestry University,Harbin 150040,P. R. China) |
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| Abstract: | An experiment was conducted to study the anti-hyperglycemic and anti-aging effects of deer antler velvet extract on diabetic mice by establishing a mouse model of diabetes induced by alloxan. The alloxan-induced diabetic mice were randomly divided into three dose groups and fed intragastrically with different doses of deer antler velvet extract (1.6,3.2,or 4.8mg/g) for four weeks. Serum glucose level,contents of MDA,glycogen and SOD,and activities of GSH-PX and CAT were determined. Compared with the model c... |
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| Keywords: | Deer antler velvet extract Mice Diabetes Serum glucose Anti-aging |
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