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A rodenticide exposed and bleeding Beagle dog with hereditary factor VII deficiency
Authors:Meredith L. Daly  VMD     Urs Giger  Dr. med. vet.  DACVIM  DECVIM  DECVCP
Affiliation:Department of Clinical Studies –Philadelphia, the Sections of Critical Care and Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA
Abstract:Objective: To report a complex presentation of an acquired and hereditary coagulopathy in a dog. Case summary: A 5‐year‐old spayed female Beagle presented for lethargy, anorexia, cough, and stiff gait, and was diagnosed with a spontaneous hemothorax. The patient recovered from this bleeding episode suspected to be secondary to anticoagulant rodenticide intoxication, but was subsequently diagnosed with factor VII (FVII) deficiency, a hereditary coagulopathy. Diagnostic approach and management of FVII deficiency is described. New or unique information provided: This paper describes an unusual presentation of an inherited hemostatic disorder. Utilization of available screening and diagnostic tools, and appropriate interpretation of test results facilitate identification and management of this inherited coagulopathy.
Keywords:coagulopathy    congenital    hemothorax    PCR test
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