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SARS冠状病毒感染恒河猴血常规及血生化的检测
引用本文:王薇,杨占秋,钟琼,周俊.SARS冠状病毒感染恒河猴血常规及血生化的检测[J].动物医学进展,2004,25(6):85-86.
作者姓名:王薇  杨占秋  钟琼  周俊
作者单位:武汉大学医学院病毒学研究室,湖北武汉,430071;武汉大学医学院病毒学研究室,湖北武汉,430071;武汉大学医学院病毒学研究室,湖北武汉,430071;武汉大学医学院病毒学研究室,湖北武汉,430071
摘    要:观察SARS冠状病毒 (SARS CoV)感染对恒河猴的血常规及各项血生化指标的影响。采集 6只恒河猴感染SARS CoV前后的血液样本 ,测定血常规及各项血生化指标 ,对测定结果作统计学处理。结果表明 ,感染SARS CoV后RBC、WBC、PLT、LYM等血液学指标降低。ALT、AST、Cr等血液生化值明显升高。感染SARS CoV后恒河猴血常规及血生化的变化与人类相似

关 键 词:SARS冠状病毒  恒河猴  血常规  血生化
文章编号:1007-5038(2004)06-0085-02
修稿时间:2004年6月14日

The Detection of Blood Routine and Biochemical Indexes in Macaca rhesus Infected with SARS-Coronavirus
WANG Wei,YANG Zhan-qiu,ZHONG Qiong,ZHOU Jun.The Detection of Blood Routine and Biochemical Indexes in Macaca rhesus Infected with SARS-Coronavirus[J].Progress In Veterinary Medicine,2004,25(6):85-86.
Authors:WANG Wei  YANG Zhan-qiu  ZHONG Qiong  ZHOU Jun
Abstract:The changes of blood routine and biochemical indexes in Macaca rhesus were explored before and after infection of severe acute respiratory syndrome associated coronavirus (SARS-CoV). Blood samples were obtained and analysed from 6 Macaca rhesus before and after infection of active SARS-CoV. The average value,standard deviation and t-test value were obtained and analysed by statistic method. The counts of RBC,WBC,PLT,LYM showed significant reduction(P<0.05) in Macaca rhesus after infection of active SARS-CoV. The values of ALT,AST,Cr showed remarkably significant increase(P<0.01) in Macaca rhesus after infection of active SARS-CoV. The results indicated that the changes of hematoliogc and biochemical indexes pre- and post-infection of SARS-CoV in Macaca rhesus were similar to those in human.
Keywords:SARS-CoV  Macaca rhesus  hematologic examination  biochemical indexes
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