猪伪狂犬病病毒gE蛋白在野毒诊断中的应用进展

Application Progress of Procine Pseudorabies Virus gE Protein in the Wild-type Virus Diagnosis

With mass immunization application of pseudorabies virus （PRV） gE gene deleted attenuated vaccine in China, it played an important role in prevention and control of porcine pseudorabies, meanwhile it also needed to establish a differential diagnosis technology for gE gene deleted vaccine matching to eliminate virus affected swine and reduce immune pigs to be killed, and gradually realized the purification of PRV. With the gradual progress of molecular biology and immunology, molecular biological and serological diagnosis methods based on PRV gE protein continuously developed and improved. In this paper, recent study on various molecular and serological diagnosis methods of gE protein based on the current situation and development prospect were reviewed, in order to provide reasonable scientific basis for diagnosis and prevention of PRV in China.