I型鸭疫里默氏杆菌荚膜免疫的研究

用盐浸法提取了I型鸭疫里默氏杆菌（RA）的荚膜，并制成油佐剂疫苗。其免疫原性测定结果表明：用荚膜粗提物免疫雏鸭可得到很好的免疫保护效果（9／10）。同时进行了RA荚膜油佐剂疫苗与各常规佐剂疫苗的免疫效力比较，免疫保护效果依次为：英膜油乳剂苗、油乳剂灭活苗、蜂胶灭活苗、铝胶RA灭活苗、无佐剂RA灭活苗。结果显示，鸭疫里默氏杆菌英膜免疫的研究为进一步研制亚单位疫苗打下基础。

Study on Riemerella anatipestifer (I) Capsular Polysaccharide Vaccine

In this study, Capsular Polysaccharide were extracted by high-concentraction NaCl, and developed the oil-adjuvant vaccine to vaccinate the 4-day-ducklings. The result of potency test for this vaccine showed that Capsular Polysaccharide vaccine had good protective efficiency (9/10). The potency comparative test of this vaccine with other adjuvant Riemerella anatipestifer (RAI) inactivated vaccines were done in the same time. The best one was Capsular Polysaccharide oil-adjuvant vaccine and the other successively were oil-adjuvant inactivated vaccine, propolis-adjuvant inactivated vaccine, aluminium hydroxide -adjuvant inactivated vaccine and no-adjuvant inactivated vaccine.