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Withanolides and related ergostane-type steroids as antifeedants for larvae ofEpilachna varivestis (Coleoptera: Chrysomelidae)
Authors:K R S Ascher  H Schmutterer  E Glotter  I Kirson
Institution:1. Institute of Phytopathology and Applied Zoology, Justus-Liebig University, Giessen, West Germany
3. Dept. of Agricultural Biochemistry, Faculty of Agriculture, The Hebrew University of Jerusalem, Rehovot, Israel
4. Dept. of Organic Chemistry, The Weizmann Institute of Science, Rehovot, Israel
Abstract:Eight steroids isolated from solanaceous plants (Physalis, Withania andNicandra species) were investigated as to their antifeedant efficacy for L4 larvae ofEpilachna varivestis Muls. (Coleoptera). Nicalbin A (VII) was a potent antifeedant, but at high concentrations it was also toxic to this insect. Other active compounds were withanolide E (I), 4β-hydroxywithanolide E (II), 5β, 6β-epoxy-1β, 14α, 17β, 20α-tetrahydroxywith-24-enolide (III), Nic-1 (nicandrenone, VI) and nicalbin B (VIII). These results were quite different from the spectrum of activity of the withanolides against larvae ofSpodoptera littoralis (Boisd.) (Lepidoptera) found in a previous study.
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