Acute phase proteins assessment for an early selection of treatments in growing calves suffering from bronchopneumonia under field conditions |
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Authors: | Humblet M-F Coghe J Lekeux P Godeau J-M |
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Affiliation: | Biochemistry Unit, Department of Functional Sciences, Faculty of Veterinary Medicine, University of Liège, Blvd de Colonster, 20, Bat. B 42, 4000 Liège-Sart Tilman, Belgium. mfhumblet@ulg.ac.be |
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Abstract: | Blood samples were taken from calves with respiratory disease the first day of examination for determination of the serum concentration of haptoglobin, fibrinogen, alpha-2- and gamma-globulins, and albumin. A clinical examination was performed daily for the duration of the disease. The animals were retrospectively classified in two categories: those animals requiring no treatment or antibiotics alone (group A), and antibiotics associated to anti-inflammatory drugs (group B). The serum proteins were tested in order to check whether they were able to distinguish, on the first day of clinical examination, between calves requiring anti-inflammatory treatment (group B) or not (group A). About 80% of calves were properly classified in both groups by the combined use of the two serum proteins haptoglobin and fibrinogen: these two proteins, and especially haptoglobin, were useful for the identification of calves requiring an anti-inflammatory treatment. |
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Keywords: | Haptoglobin Fibrinogen Inflammation Bronchopneumonia Treatment |
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