Clinical and echocardiographic features of mild mitral valve regurgitation in 108 horses |
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| Authors: | Alexandra Imhasly Peter R Tschudi Christoph W Lombard Vincent Gerber |
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| Institution: | 1. Equine Hospital, Department of Clinical Veterinary Medicine, Vetsuisse-Faculty of the University of Berne, 3012 Berne, Switzerland;2. Small Animal Clinic, Department of Clinical Veterinary Medicine, Division of Cardiology, Vetsuisse-Faculty of the University of Berne, 3012 Berne, Switzerland;1. Clinical Department of Companion Animals and Equids, Faculty of Veterinary Medicine, Equine Teaching Hospital, University of Liège, Liège, Belgium;2. GIGA (Groupe Interdisciplinaire de Génoprotéomique Appliquée), Transgenics platform, University of Liège, Liège, Belgium;3. Biostatistics, Bioinformatics, Economics and Animal Selection, Department of Animal Production, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium;4. Equine Sports Medicine Practice (ESMP), Waterloo, Belgium;1. Equine Department, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland;2. Graduate School for Cellular and Biomedical Sciences, University of Bern, Freiestrasse 1, 3012 Bern, Switzerland;3. Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland;4. Center for Integrative Human Physiology (ZIHP), University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland;5. Center for Applied Biotechnology and Molecular Medicine (CABMM), University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland;1. Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 1060 William Moore Drive, Raleigh, NC 27606, USA;2. Veterinary Clinical Sciences, The Ohio State University, Columbus, OH, USA |
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| Abstract: | The clinical and echocardiographic characteristics of 108 horses with echocardiographically confirmed mild mitral valve regurgitation (MR) were investigated along with its clinical progression. Follow-up consisted of a re-examination of 28 horses and questionnaires were used to obtain information on a further 43 cases. Thirty-seven horses with mild MR were lost to follow-up. Horses with mild MR were re-examined between 2 and 9 years (3.8 ± 1.8 years) following first presentation, with mild MR still present and a small, but statistically significant (P = 0.049) increase of left ventricular diameter in end-diastole. These results suggested that mild MR has a good mid-term prognosis in sport and pleasure horses. |
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