食用菌多糖抗运动疲劳研究进展

采用文献资料法对食用菌多糖抗运动疲劳的研究进展情况进行了研究。结果表明:食用菌多糖提取方法不同而食用菌多糖的提取率也不相同,超声波法+复合酶法及微波法提取食用菌多糖提取率较高,2种方法科学合理的结合提取食用菌多糖以及不同产地、品种和不同部位提取率是未来学者们需要研究的领域;目前,只是对极少部分食用菌多糖抗运动疲劳进行了研究,研究对象(动物)、模型、指标、评价单一而没有确定最佳剂量的时间而没确定的量。为此,提出了未来应加强和重视食用菌多糖抗疲劳运动多食用菌、多对象(尤其是人)、多模型、多指标、多评价、最佳剂量的研究以及量-效、构-效关系的研究建议。     

加工现场微机控制系统抗干扰的研究

针对制造业加工现场的环境特点，分析了微机控制系统的干扰来源和途径，介绍了实用的抗干扰措施。实践证明：这些软硬件抗干扰措施的综合运用，使自动化加工中微机控制系统的稳定性得到了较大的提高。     

引起笼养蛋鸡疲劳症的主要因素研究

本试验以营养因子、产蛋率、钙源、笼养生态等角度对笼养蛋鸡疲劳症进行综合研究,寻找引起笼养蛋鸡疲劳症的主要因素及减少笼养蛋鸡疲劳症的途径。     

Pharmacokinetics of multiple doses of transdermal flunixin meglumine in adult Holstein dairy cows

A transdermal formulation of the nonsteroidal anti‐inflammatory drug, flunixin meglumine, has been approved in the United States and Canada for single‐dose administration. Transdermal flunixin meglumine was administered to 10 adult Holstein cows in their second or third lactation at the label dose of 3.33 mg/kg every 24 hr for three total treatments. Plasma flunixin concentrations were determined using high‐pressure liquid chromatography with mass spectroscopy (HPLC ‐MS ). Pharmacokinetic analysis was completed on each individual animal with noncompartmental methods using computer software. The time to maximum drug concentration (T max) was 2.81 hr, and the maximum drug concentration was 1.08 μg/ml. The mean terminal half‐life (T½) was determined to be 5.20 hr. Clearance per fraction absorbed (Cl/F) was calculated to be 0.294 L/hr kg^?1, and volume of distribution of fraction (V z/F ) absorbed was 2.20 L/kg. The mean accumulation factor was 1.10 after three doses. This indicates changes in dosing may not be required when giving multiple doses of flunixin transdermal. Further work is required to investigate the clinical efficacy of transdermal flunixin after multiple daily doses.     

Histological and immunohistochemical evaluation of granulosa cells during different stages of folliculogenesis in bovine ovaries

Bovine granulosa cells (GC) vary in their morphological aspect during different stages of folliculogenesis. In this study, 10 morphologically normal bovine ovaries were collected to study the structural aspects of different stages of GC using intermediate filament protein antibodies including cytokeratin AE1/AE3 (AE1/AE3), vimentin, nectin‐4 and desmin. Hormonal immunolocalization was assessed using the immunomarkers anti‐Müllerian hormone (AMH) and inhibin alpha. In addition, tumour markers and proliferation markers using c‐erbB‐2 oncoprotein and proliferating cell nuclear antigen, respectively, were investigated. The immunolabelling of AE1/AE3 in GC was strongest in the early follicle stage and gradually decreased when reaching the Graafian follicle stage. Its immunolabelling increased again as the stage progressed from stage I to stage III. The immunolabelling of inhibin alpha was inversely proportional to that of AE1/AE3 in the developing ovarian follicles as their immunolabelling is opposite to each other during folliculogenesis. AMH was immunopositive in almost all GC stages in different intensities and percentages, except for some negative staining in the atretic IV follicles. The atretic IV follicle is a unique type of atretic follicle that shows Call‐Exner body formation, which was mainly found in older cows in this study. The distinct patterns of immunoreactivity for various types of immunomarkers in the different GC stages will play an important role in diagnostic assistance of various follicle conditions, including cystic ovaries and GC tumours.     

松茸多糖对缓解运动员有氧运动疲劳恢复应用研究

通过分析松茸多糖对有氧运动所产生的一系列良好效果,进行松茸多糖对运动员疲劳恢复的相关研究,松茸多糖主要涉及到运动员运动过程当中,其机体所产生的血清尿素(BU)含量、血清丙二醛(MDA)含量、血清肌酸激酶(CK)、血清超氧化物歧化酶(SOD)以及谷胱甘肽过氧化物酶(GSH-PX)活性的变化。相关研究结果表明,松茸多糖能够对此起到良好的修复作用,有效抑制运动过后所产生的骨骼肌损伤,增强运动员机体抗氧化能力,从而达到恢复疲劳的作用。     

EFFECT OF HIGH LOADS IN THE BRIDGE LOAD SPECTRUM ON FATIGUE CRACK GROWTH OF 16 Mn STEEL

This paper studies an effect of high loads in Rayleigh distribution random load-ing on fatigue crack growth wi th 16 Mn steel compact tenion specimen,The results show that thehigh loads in the load spectrum close to service load of steel bridges accelerate crack growth and re-duce crack growth life,Lives predicted with constant amplitude da/dn data and equivalent loads arequite in agreement with test lives.