The Effect of Dietary Sulphate Copper Supplementation on Growth Performance,Intestinal Digestive Enzymes and Absorptive Transporters in Weanling Pigs1

The experiment was conducted to as- sess the effects of dietary supplementation of Cu on the growth performance, digestive enzymes, tissue minerals and absorptive transporters in small intestinal mucosa of weanling pigs. One hundred crossbred pigs weaned at 28 ＋ 2 d of age were assigned randomly to one of the following diets with 5 replicates：corn-soy- bean basal diet with 10,100,175,250 mg/kg of Cu as CuSO4·5H20. The results showed that 250 mg/kg Cu had a positive effect （ P 〈 0.05） on average daily gain, daily feed intake and ratio of gain/feed. Com- pared to 10 mg/kg Cu, higher Cu had significant effect on the apparent digestibility of protein and fat （P 〈 0.05 ）. The supplementing of Cu improved am- ylase and lipase activity in jejunum content and lipase in pancreas （ P 〈 0.05） and had no effect on intestinalmorphology. The liver Cu elevated approximately 4- fold in pigs fed diet with 250 mg/kg Cu compared with pigs fed diet with 10 mg/kg Cu, no increases were observed in pigs receiving the lower level of Cu （100 and 175 mg/kg）. Both Fe and Zn contents in kidney and liver were not affected by Cu supplemen- tation. There was no positive effect （ P 〉0.05） of Cu supplementation on PepT1 （peptide transporter 1 ） and SGLT1 （sodium/glucose cotransporter） mRNA abundance in intestinal mucosa. However, higher sup- plementing level （250 mg/kg） significantly elevated the DMT1 （divalent metal transporter） mRNA abun- dance in duodenum mucosa. These results suggested that dietary supplementation with 250 mg/kg Cu could improve growth performance, nutrient digestibil- ity and intestinal enzyme activities of weanling pigs.     

烟酸和烟酸铬对断奶犊牛应激的影响

选用三月龄断奶荷斯坦犊牛30头,将其等分为三组,对照组为基础日粮,烟酸组和烟酸铬组分别在基础日粮中添加400 mg/kg的烟酸和6.4 mg/kg的烟酸铬.结果表明:烟酸和烟酸铬在前10 d对犊牛的增重影响不明显(P>0.05);20～30 d,烟酸组和烟酸铬组的平均日增重比对照组分别提高5%和27.6%;30～40 d,烟酸组和烟酸铬组的平均日增重比对照组分别提高12.8%和18.11%;而最后一个阶段,烟酸组和烟酸铬组的平均日增重比对照组分别提高8.9%和7.45%.试验期间,烟酸铬组与对照组相比提高T3、T4、生长激素、胰高血糖素水平分别为25.68%(P<0.05)、17.31%、6.73%、9.03%;烟酸组与对照组相比提高T3、T4水平分别为11.5%、12.7%.