ULTRASONOGRAPHIC IDENTIFICATION AND CHARACTERIZATION OF SPLENIC NODULAR LIPOMATOSIS OR MYELOLIPOMAS IN CHEETAHS (ACINONYX JUBATUS)

A total of 44 live cheetahs were examined sonographically between 1989 and 1994. Seventeen of these animals originated from 4 European facilities, the other 27 cheetahs were examined in 3 facilities in Namibia. Evaluation of the cheetahs included a clinical examination, abdominal ultrasound, and complete blood work. Splenic myelolipomas were diagnosed sonographically in 11 cheetahs. In 7 cheetahs the diagnosis was confirmed at necropsy. Nine of the 14 cheetahs in Europe had myelolipomas in the spleen, while in the African cheetahs there were only 2 animals with myelolipomas. Histologically these lesions were characterized by fatty nodules. A more fitting term of Nodular Lipomatosis of the spleen is therefore suggested. All cheetahs with nodular lipomatosis of the spleen, had concurrent chronic diseases at necropsy. An indicator function of splenic nodular lipomatosis for chronic disease and/or stress is possible.     

Caecal lipomatosis as a cause of colic in a 9‐year‐old gelding

Lipomatosis is an uncommon cause of colic. This case report details the pre‐ and intraoperative findings of a 9‐year‐old gelding, presented with acute abdominal pain. Exploratory laparotomy revealed a massive fatty infiltrate involving an extensive portion of the base and mid‐body of the caecum. To the authors' knowledge, this is the first report of an infiltrative lipomatous lesion of the equine caecum.     

Lipomatosis of axillary lymph nodes in a cynomolgus monkey (Macaca fascicularis)

Lipomatosis of lymph nodes is defined as the replacement of the lymphatic parenchyma by adipose tissue which grows in the node from the hilus toward the cortical zone. In humans, it is considered as part of the normal aging process and is common in obese patients, but there are no reports in non-human primates. In this report, we describe the first case of lymph node lipomatosis in the bilateral axillary lymph nodes of a young adult cynomolgus monkey. Macroscopically, there were no apparent abnormalities in the axillary lymph nodes on either side, and their volumes were unchanged. At the cut surface, pale yellow fat-like tissue was observed in the medullary area. Histopathologically, well differentiated adipocytes replaced a large part of the lymphatic parenchyma in the area from the hilus to the medulla without any malignant findings. Based on these findings, the patient was diagnosed with lipomatosis of the lymph nodes.     

IMAGING DIAGNOSIS—CONCENTRIC PERIRADICULAR LIPOMA CAUSING LUMBAR NERVE ROOT COMPRESSION IN A DOG

An 11‐year‐old, male neutered Jack Russell Terrier was presented with a nerve root signature of the right pelvic limb. Magnetic resonance imaging revealed a well demarcated, ovoid, extramedullary mass at the level of the L7 vertebral body. This showed, compared to normal spinal cord, hyperintense signal on T1‐ and T2‐weighted images, which was suppressed on gradient echo short tau inversion recovery (GE‐STIR) images. Additionally, the mass was characterized by a fat density on computed tomography images. Histopathology of the surgically excised mass was consistent with concentric periradicular lipoma, which has not been described in domestic animals yet.     

Epidemiological survey,general blood biochemistry,and histological examination of slaughtered heavy horse breeds with hemorrhage in the adipose tissue in the crest of the neck

Fifty-four slaughtered horses were classified into groups having adipose tissue in the crest of the neck with or without hemorrhage (AH and NH groups, respectively). Blood biochemical tests (Alb, TP, T-bil, GOT, GPT, LDH, T-cho, and BUN) and an epidemiological survey (age, gender, weight, origin, breed, BCS, CNS, and hoof disease) were performed. T-bil tended to be high, while the other parameters were normal. Weight, BCS, and CNS were higher in the AH group (P<0.05). GOT was lower in the AH group (P<0.05). It was suspected that the horses in the AH group had lipomatosis. It was assumed that the adipose tissue of the horses in the AH group contained damaged capillaries, and inflammation was confirmed based on evidence of macrophages and lymphocytes.     

Case report of atypical infiltrative lipomatosis of the equine mesojejunum

A 25‐year‐old mare was examined for persistent colic. Over the previous month, the mare had experienced several episodes of mild recurrent colic. The episode of colic persisted for 18 h and the pain became unresponsive to analgesic therapy. Euthanasia was undertaken. Post mortem examination revealed an atypical infiltrative lipoma of the mesojejunum, confirmed histopathologically. To the authors' knowledge, this is the first case report of a diffuse infiltrative lipoma of the equine mesojejunum.     

Liposarcoma or invasive lipomatosis in flower horn fish,hybrid cichlid: clinical,radiological, ultrasonographical and histopathological study

Liposarcoma or invasive lipomatosis affecting three indoor aquarium fish (flower horn fish, hybrid cichlid) is characterized, by the presence of mature adipocytes of variable sizes and by an invasive behaviour, which affected internal organs and eyes of all cases. Detailed macroscopic, radiological, ultrasonographical and histopathological features are presented. All fish had bilateral exophthalmia with some masses around the eyes. Ultrasonography confirmed the presence of hyperechoic masses in the eyes. Histopathology of all cases described the presence of variable‐sized adipose cells in the eyes. The suggested diagnosis is well‐differentiated liposarcoma or invasive lipomatosis. This is the first report of liposarcoma or invasive lipomatosis in flower horn fish, hybrid cichlid.     

Lipomatosis of the canine parotid gland: case report with a literature review

In this report, we describe a case of lipomatosis in the left parotid gland of an eight-year-old female Shetland sheepdog and review the relevant literature. Preoperative diagnosis of lipomatosis with Tru-Cut biopsy presented difficulties in this case. The postoperative diagnosis was based on the gross appearance of a non-infiltrative, circumscribed swollen mass in the parotid gland and the histological appearance of normal adipocytes that infiltrated into the parotid gland without involving surrounding structures. Additionally, flotation of the whole parotid gland in formalin solution together with well-maintained residual lobulation and a well-maintained configuration on the cut surface were identified as subsidiary characteristics of lipomatosis of the parotid gland. Lipomatosis of the parotid gland has been rarely reported in dogs and is a poorly understood condition.     

NODULAR FAT NECROSIS IN THE FELINE AND CANINE ABDOMEN

The radiographic appearance of nodular fat necrosis is described in ten cats and one dog. The most common radiographic sign was the presence of a focal mineralized circular to oval soft tissue mass in the abdominal fat as present in 9 cats. These masses had a distinct eggshell-like rim encapsulating the lesion. In one cat and one dog multiple masses were present, without radiographic signs of mineralization. Abdominal ultrasound was performed in three cats and one dog, findings included the presence of hyperechoic masses with associated acoustic shadowing, some with a hypoechoic centre. Almost all animals were old and obese. In three cats and one dog, changes were confirmed with biopsy or post mortem examination. Lesions having the appearance of those in this paper are most likely incidental findings and should not be confused with abdominal masses of neoplastic origin. Ultrasound can be helpful in identifying such lesions.