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1.
中草药多糖免疫调节剂研究进展 总被引:4,自引:0,他引:4
中草药多糖是增强机体免疫的物质基础 ,对促进和恢复机体免疫机能的作用极为明显。它的重要性正引起广泛关注。文章主要从中草药多糖的研究状况、开发应用及存在问题等方面进行了探讨 ,对于进一步了解中草药多糖在生理和病理过程中的作用及其免疫调节机制有一定意义 相似文献
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K. S. Venturini M. F. Sarcinelli M. A. Baller T. C. Putarov E. B. Malheiros A. C. Carciofi 《Journal of animal physiology and animal nutrition》2018,102(4):1077-1087
Soya bean protein concentrate (SPC) with two particle sizes were evaluated on extrusion parameters, kibble formation, digestibility and palatability of dog foods. Eight diets were extruded: PBM—control diet based on poultry by‐product meal (PBM); GM—a diet in which corn gluten meal (GM) replaced 45% of the diet protein; cSPC15%, cSPC30% and cSPC45%—diets in which SPC of coarse particle size (600 μm) replaced 15%, 30% and 45% of the diet protein; and sSPC15%, sSPC30% and sSPC45%—diets in which SPC of small particle size (200 μm) replaced 15%, 30% and 45% of the diet protein. The digestibility of nutrients was evaluated for the PBM, GM, cSPC45% and sSPC45% diets, using six dogs per food. The PBM, GM and cSPC45% diets were compared for palatability. Data were submitted for analysis of variance, and the means were compared by polynomial contrasts or Tukey's test (p < .05). The cSPC increased the specific mechanical energy (SME) application, extrusion temperature and pressure linearly, resulting in lower kibble density and higher expansion and starch gelatinization (SG) (p < .01). When comparing the PBM, GM, cSPC45% and sSPC45% diets, higher SME, extrusion temperature and pressure, SG and kibble expansion were verified for the cSPC45% diet (p < .05). The DM, fat and crude protein digestibility were similar among diets. Faecal pH, ammonia and lactate did not differ, demonstrating that the removal of oligosaccharides and soluble non‐starch polysaccharides of SPC produces an ingredient with mostly non‐fermentable fibre. Dogs preferred the PBM to the GM diet (p < .05), but consumed the PBM and cSPC45% foods equally. In conclusion, SPC exhibited good extrusion functionality, favouring kibble expansion and SG, with high digestibility, similar to that of PBM. The removal of soluble compounds from soya beans resulted in an ingredient with low fermentable fibre content, which did not alter faecal formation or characteristics. 相似文献
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筛选出对中药复方免疫增强剂多糖具有较好的吸附解吸效果的大孔树脂。通过静态吸附及解吸试验、动态吸附及解吸试验,利用苯酚 硫酸法跟踪检测多糖质量浓度,以吸附率与解吸率为评价指标,初步研究AB 8、LSA 5B、DM 18、CAD 40、LX 1、D941型大孔树脂对中药复方免疫增强剂中多糖的吸附及解吸性能。结果表明,在6种大孔树脂中, AB 8对中药复方免疫增强剂多糖的动态吸附率和解吸率最高,分别为54%和90%。说明AB 8型大孔树脂可以作为分离纯化多糖的材料。 相似文献
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Sulfated polysaccharides produced by microalgae, which are known to exhibit various biological activities, may potentially serve as natural antioxidant sources. To date, only a few studies have examined the antioxidant bioactivity of red microalgal polysaccharides. In this research, the effect of different salts on the antioxidant activities of two red microalgal sulfated polysaccharides derived from Porphyridium sp. and Porphyridium aerugineum were studied in a soy bean-based infant milk formula. Salt composition and concentration were both shown to affect the polysaccharides’ antioxidant activity. It can be postulated that the salt ions intefer with the polysaccharide chains’ interactions and alter their structure, leading to a new three-dimensional structure that better exposes antiooxidant sites in comparison to the polysaccharide without salt supplement. Among the cations that were studied, Ca2+ had the strongest enhancement effect on antioxidant activities of both polysaccharides. Understanding the effect of salts on polysaccharides’ stucture, in addition to furthering knowledge on polysaccharide bioactivities, may also shed light on the position of the antioxidant active sites. 相似文献
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金针菇多糖的提取及含量测定 总被引:2,自引:0,他引:2
探讨了用温度70℃热水提取、sevag法除蛋白、乙醇分级沉淀提取金针菇多糖,以及用硫酸-蒽酮法测定其含量的方法。该方法测得多糖的总收率为金针菇湿质量的0.11%,测定多糖的线性范围为1~16μg/mL,对金针菇多糖含量测得的RSD小于2.24%,回收率为97.6%~102.8%。 相似文献
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In the course of searching immunodulators from natural herbal sources,the polysaccharide has been isolated from the water extract of duckweed(Herba Spirodelae seu Lemnae).The authors aim at investigating the methods that determine the content of total saccharides in the mixture,accordingly,to be used as a quality control in the procedure of producing polysaccharides from duckweed.The contents of saccharides in the extraction were mensurated by spertrophotometry of sulphuric acid-phenol and sulphuric acid-anthrone.And the validitiy of methods was evaluated through some indexes such as linearity and range,precision,stability,and accuracy.The results reveal the methods are convenient,rapid,accurate,and high sensitive,thereby leading to a wide and effective use in determining the saccharides contents in polysaccharides extraction from Herba Spirodelae seu Lemnae. 相似文献
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【研究目的】研究并优化乙醇提取绵茵陈中绿原酸的最佳操作参数;【方法】以绵茵陈为原料,通过单因素试验、正交试验和方差分析确定最佳提取工艺;【结果】结果表明:乙醇提取绵茵陈中绿原酸的效果较好;确定的最佳工艺参数乙醇浓度为60%、料液比1:25、提取温度60℃、提取时间1.5h;【结论】采用60%乙醇可以很好提取绵茵陈中的绿原酸。 相似文献
10.
Yi Qi Jingyi Zhou Xiaoqin Shen Meram Chalamaiah Simin Lv Hui Luo Liang Chen 《Marine drugs》2022,20(1)
Peanut worms (Sipunculids) are unsegmented marine worms that usually inhabit shallow waters. Peanut worms are good source of bioactive compounds including peptides and polysaccharides. Many recent studies have investigated the bioactive properties of peptides and polysaccharides derived from peanut worms in order to enhance their applications in food and pharmaceutical industries. The peptides and polysaccharides isolated from peanut worms have been reported to possess anti-hypertensive, anti-oxidant, immunomodulatory, anti-inflammatory, anti-cancer, anti-hypoxia and wound healing activities through the modulation of various molecular mechanisms. Most researchers used in vitro, cell culture and animal models for the determination of bioactivities of peanut worm derived compounds. However, studies in humans have not been performed considerably. Therefore, it is important to conduct more human studies for better utilization of marine bioactive compounds (peptides and polysaccharides) derived from peanut worms. This review mainly focuses on the bioactive properties of peptides and polysaccharides of peanut worms and their molecular mechanisms. 相似文献