甘肃白猪性畸形及其对生产性能的影响

为了配合育种工作,作者采用常规染色体制备方法,对96头甘肃白猪及其杂交猪的染色体作了研究。检出核型为38,XY的雌性个体2头。染色体G—带和性染色质分析的结果表明它们具有1条Y染色体和1条X染色体。对这2头间性个体的肥育性能、胴体成绩和肉品质三项指标测定结果表明,间性个体与正常个体无显著差异。由于这2头个体均与武武品系有关,所以在这一品系的选育中应给予高度重视。     

SRY-positive 78, XY ovotesticular disorder of sex development in a wolf cloned by nuclear transfer

Recently, we reported the three wolves cloning with normal karyotype from somatic cells of endangered male gray wolves (Canis lupus), but one wolf had female external genitalia. In this study, we conducted further clinical, histological, and genetic analyses. This cloned wolf had a normal uterus but developed ovotestis. Through molecular analysis of the SRY gene, a mutation in the coding sequence of SRY gene could be excluded as a cause of intersexuality. This is the first report of a cloned wolf with a 78, XY ovotesticular disorder affecting sexual development characterized by bilateral ovotestes.