Transplantation of adipose derived mesenchymal stem cells for acute thoracolumbar disc disease with no deep pain perception in dogs

Thirty-four dogs with no deep pain perception due to acute thoracolumbar intervertebral disc disease underwent decompression surgery within 1 week of diagnosis. All dogs underwent hemilaminectomy. Adipose derived mesenchymal stem cells (AD-MSCs) were transplanted into the injured spinal cord parenchyma for the AD-MSCs transplant dogs. Long-term outcome was evaluated at the end of the follow-up period (> 6 months). AD-MSCs combination treatment showed better recovery outcomes compared to decompression surgery alone. These results indicate that this stem cell therapy is a potential therapeutic strategy to overcome the limitations of treatment for spinal cord injury in clinical medicine.     

Thoracolumbar lateral corpectomy for treatment of chronic disk herniation: technique description and use in 15 dogs

OBJECTIVE: To describe a technique for thoracolumbar lateral corpectomy and to evaluate its use for treatment of chronic thoracolumbar disk disease in dogs. STUDY DESIGN: Retrospective study. ANIMALS: Fifteen dogs with signs of chronic thoracolumbar disk herniation. METHODS: After a dorsal or lateral approach to the spine, a lateral slot was created in 2 adjacent vertebral bodies on either side of the herniated disk and extruded/protruded material was removed. Data collected included history, duration of clinical signs, presurgical assessment of neurologic status, postsurgical neurologic status, complications, and outcome. RESULTS: Ambulatory capacity was maintained or regained, and neurologic status improved by 1 grade (3 dogs), 2 grades (8), 3 grades (2), or 4 grades (2). Eleven dogs were considered free of disease. A seroma in 1 dog was the sole complication observed. CONCLUSIONS: Lateral corpectomy permits relatively easy removal of protruded-extruded disk material from within the vertebral canal in chronic disk disease without further iatrogenic injury to the spinal cord. CLINICAL RELEVANCE: Lateral corpectomy is an alternative to dorsal decompression for treatment of ventral and lateroventral thoracolumbar chronic disk disease in dogs.     

Syringomyelia: current concepts in pathogenesis, diagnosis, and treatment

Syringomyelia is a condition that results in fluid-containing cavities within the parenchyma of the spinal cord as a consequence of altered cerebrospinal fluid dynamics. This review discusses the history and the classification of the disorder, the current theories of pathogenesis, and the advanced imaging modalities used in the diagnosis. The intramedullary pulse pressure theory (a new pathophysiologic concept of syringomyelia) also is presented. In addition, the current understanding of the painful nature of this condition is discussed and the current trends in medical and surgical management are reviewed.     

Diagnosis and surgical treatment of epidural neoplasms in two ataxic horses

Two cases of ataxia caused by epidural neoplasia diagnosed with myelography and histopathology are presented in this report. One horse was diagnosed with lymphohistiocytic lymphosarcoma and the other with haemangiosarcoma. In both cases, subtotal dorsal decompression was performed as part of their treatment protocol. One horse was subjected to euthanasia immediately after surgery; however, the other horse recovered well, with no gait abnormalities and a normal myelographic dye column seen at 6 months post surgery. Although both horses were ultimately subjected to euthanasia, subtotal dorsal decompression provides a potential surgical treatment for epidural neoplasia.     

丘陵山区重力式供水设置网中减压储水装置的管网优化分析

针对丘陵山区村镇重力式供水管网投资浪费大、运行可靠性差问题,进行了管网增设减压储水装置的优化对比分析.结果表明增设该装置后,可使同一管网低区压力降低到正常使用压力,上游管道时高峰流量消减到平均时流量,从而大幅减少管网投资并提高了供水可靠性.     

液化石油气储罐快速降压过程的初步模型

对液化石油气容器在气相壁上出现裂口后引发的快速降压过程建立了初步模型,分析了液体中气泡生成过程,产按气泡半径 是否超过临界半径,分两个阶段分别讨论了气相和液相空间各物理量的变化过程,通过具体计算实例,最终得出了过程中可能发生压力下降然后急剧上升这一现象的结论,并分析了初始温度（初始压力）,初始充注量,热流密度,裂缝面积对于上述物理过程的影响。     

平原水库利用排渗减压技术预防库外农田浸没

由于黄泛区平原水库坝基一般为软弱透水地基,坝基经过防渗处理后,坝基渗透稳定,渗漏量得到有效控制,但坝基不可避免的还有一定数量的渗漏量,下游坝址外尚保留一定的剩余水头,渗水如果不及时排走,会导致区域地下水位升高,造成库外农田浸没。笔者以山东聊城发电厂新厂引黄调蓄水库为依托,阐述平原水库如何用排渗沟和减压井联合排渗减压技术防止库外浸没和土地盐碱化。减压井和排渗沟联合排渗减压是降低地下水位、防止库外浸没的有效措施。     

长输天然气管道冬季冻堵防治实例

中国石化榆济输气管道在试运行过程中,因发生水合物冻堵事故,西源祠阀室、石门阀室、杨家峪阀室压力变化异常,通过分析上下游管道的运行参数和统计管道工程遗留的裸管段,初步确定两处裸管段为线路冻堵点:1#冻堵点位于西源祠阀室和石门村阀室之间的爬坡段,2#冻堵点位于石门村阀室和杨家峪阀室之间的U形弯管段。根据现场实际,在采取应急处置措施的基础上,将加注醇类抑制剂、管道天然气放空、全线降压运行和加装电伴热4种方法结合使用,很快缓解了冻堵现象,确保了管输安全。