柞蚕雄蛾粉对家兔肝脏功能的影响

柞蚕雄蛾粉在６２５－１２５ｍｇ／ｋｇ剂量范围内对家兔用药１０天，可显著降低家兔肝脏过氧化脂南的含量，增强ｒ－谷氨酰酶活性，对谷丙转氨酶、乳酶脱酶活性无明显影响。     

家蚕丝素蛋白对大鼠胆固醇代射的影响

研究了经酸解后制得的家蚕丝素蛋白氨基酸组成以及对高血脂实验鼠血清和肝脏内胆固醇及转氨酶的活性变化的影响。结果表明：所得的家蚕丝素蛋白粉氨基酸组成丰富，其中甘氨酸、丙氨酸、丝氨酸和酪氨酸含量占全部氨基酸总量的95%；家蚕丝素蛋白能显著地降低血清胆固醇含量和谷草转氨酶及谷丙转氨酶活性，提高动物肝组织中的胆固醇浓度和谷丙转氨酶的活性。     

鸡实验性急性有机磷中毒血清酶活性变化分析

选取临床健康体质量为0.8±0.07kg的三黄肉鸡24只,随机分成3个试验组和1个对照组,每组6只,其中试验、和组分别皮下一次注射氧乐果攻毒,剂量分别为35mg/kg体质量、70mg/kg体质量和140mg/kg体质量;对照组注射生理盐水。攻毒后系统观察动物急性有机磷中毒症状,采血测定体内胆碱酯酶(CHE)、碱性磷酸酶(ALP)、乳酸脱氢酶(LDH)、谷丙转氨酶(ALT)以及谷草转氨酶(AST)的活力。试验结果表明:鸡急性有机磷中毒主要表现为精神沉郁,共济失调,口角大量流涎,呼吸困难,严重腹泻和粪便带血等临床症状。攻毒组CHE3活性显著低于对照组,ALP的活性也有所降低,LDH活性升高,但ALT和AST的活性无显著变化。     

沈阳市某乳业公司奶牛营养代谢病的检查

对沈阳某乳业公司7个奶牛场的牛群进行营养代谢病抽检，从全群3000多头成母牛中共抽检350头，其中包括84头高产奶牛、77头干奶牛、92头产后牛和97头有病牛。检测内容包括血酮、血糖、CO2结合力和血中谷-丙转氨酶等4项指标。结果表明：该公司牛群在围产期存在较大的饲养和管理问题。     

苹果酸在反刍动物的应用现状

本文主要对苹果酸在反刍动物研究进展进行总结，阐述其作用机理和主要应用情况。     

N-甲基-D-天冬氨酸对肥育猪生长及激素水平的影响

选取体重51 kg左右杜长大肥育猪84头,随机分为2组,每组设3个重复,2组分别饲喂添加0、50 mg/kg N-甲基-D-天冬氨酸(NMDA)的饲粮,试猪体重达88 kg时结束饲养试验,并对猪生长性能及血液相关激素指标进行分析,结果表明50 mg/kg NMDA可以显著影响猪的生长性能及内分泌水平,试猪日增重提高9.31%(P＜0.01),料重比降低7.16%(P＜0.02);血清生长激素含量提高了92.54%(P＜0.01),IGF-I水平增加了50.68%(P＜0.05),TSH、FT 3、FT 4的浓度分别提高了78.40%(P＜0.02)、123.33%(P＜0.01)和60.58%(P＜0.03),胰岛素水平提高了62.61%(P＜0.05).由此可见,NMDA可以显著影响猪的生长及血清相关激素水平.     

铜中毒对雏鸭某些血液指标的影响

选用1日龄天府肉鸭210只,随机分为3组,分别喂以对照日粮(Cu12.16mg/kg)、铜中毒日粮(Cu850mg/kg)和铜中毒日粮(Cu1050mg/kg)。试验期7周。以血液病理学方法观察了铜中毒对雏鸭某些血液学指标的影响。结果显示铜中毒组、组雏鸭分别于2周龄和3周龄开始出现临床症状,死亡18只和5只。血液病理学变化表现为,红细胞大小不等、变形变性、坏死溶解;红细胞数量和血红蛋白含量显著降低(P<0.01),血清谷丙转氨酶、谷草转氨酶活性显著升高(P<0.05或P<0.01),血清铜蓝蛋白活性下降。结果表明,铜中毒对雏鸭的生长发育和上述血液指标影响明显。     

苓桂术甘汤对肉鸡腹水综合征的防治作用

将15日龄艾维茵肉鸡分成5组,一组在常温(21±1)℃下饲养,作为正常对照组(N);其余4组在低温(11±1)℃下饲养以诱发腹水综合征,其中模型对照组(C)不给任何药物,维生素组(V)饮水中添加VC(0.5 g/L)和VE(0.1 g/L),2个试验组(T1和T2)分别给予不同剂量(0.4和0.8 mL/kg bw)的苓桂术甘汤。结果显示,C组的腹水发病率、腹水心脏指数(AHI)、红细胞压积(PCV)、红细胞数、血红蛋白(Hb)及丙二醛(MDA)含量、血清α-羟丁酸脱氢酶(-αHBDH)、谷草转氨酶(GOT)和谷丙转氨酶(GPT)均显著高于N组;而3种抗氧化酶[超氧化物歧化酶(SOD)、过氧化氢酶(CAT)和谷胱甘肽过氧化物酶(GSH-Px)]的活性则显著降低;2个试验组及V组的上述检测指数都得到明显改善,表明苓桂术甘汤能增强肉鸡的抗氧化能力,具有防治肉鸡腹水综合征的作用。     

Study on Liver-protective Effect of Chinese Herbal Compound Probiotics on Acute Liver Injury Layers

This experiment was conducted to investigate the liver-protective effect of Chinese herbal compound probiotics (CHCP) on acute liver injury layers.One hundred and eight 1 day old hens were divided into 4 groups with 3 replicates in each group and 9 layers per replicate in trial 1.The layers in model groups Ⅰ to Ⅲ were gavaged with 10% (V/V) soybean oil solution of carbon tetrachloride (SCCl₄) according to 1,2 and 4 mL/(kg·BW) at 14,28 and 35 d,respectively.The layers in control group were gavaged with 2 mL/(kg·BW) soybean oil.In trial 2,sixty 1 d layers were divided into 5 groups:Control group (soybean oil),model control group(SCCl₄)and low-dose,middle-dose and high-dose CHCP group (SCCl₄+1‰ CHCP,SCCl₄+2‰ CHCP and SCCl₄+4‰ CHCP respectively).CHCP were used by drinking water since 7 days.SCCl₄ were gavaged according to 2 mL/(kg·BW) at 14 and 28 d.The results showed as follows:The model of layers liver damage could be built by intragastric administration of 2 mL/(kg·BW) 10%(V/V) SCCl₄ at 14,28 d respectively,with the signs of hepatic steatosis,severe vacuolar degeneration,nuclear condensation and necrosis.Compared to the model control group,the serum AST levels in low,medium and high dose CHCP groups were decreased by 4.35% (P > 0.05),7.57% (P > 0.05) and 9.79% (P < 0.05),the serum ALT levels in medium and high dose CHCP groups were decreased by 34.92% (P < 0.01),36.51% (P < 0.01),the serum total bilirubin content in medium and high dose CHCP groups were decreased by 25.49% (P < 0.01),27.45% (P < 0.01).The liver cell congestion was reduced to varying degrees in different dose CHCP groups,and the liver cell had no vacuoles,arranged in neat rows,abundant cytoplasm and uniform in different dose CHCP groups.In conclusion,2‰,4‰ CHCP could reduce hepatocyte necrosis,decrease the serum activities of ALT,AST and total bilirubin levels,and had protective effect on hepatic injury induced by SCCl₄.