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Matos MF Leite LI Brustolim D de Siqueira JM Carollo CA Hellmann AR Pereira NF da Silva DB 《Fitoterapia》2006,77(3):227-229
The cytotoxic effects of seven constituents isolated from Duguetia glabriuscula were evaluated against Hep2 human larynx carcinoma cells. The cytotoxicity exhibited by beta-sitosterol was as strong as that of cis-platin. (+)-Alloaromadendran-10,14beta-diol caused inhibition of cellular growth with IC50 values lower than 25 microg/ml, a feature that was considered as revealing significant activity. Polycarpol showed borderline cytotoxicity, whereas the other compounds were inactive. 相似文献
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