我国热带地区藤黄科植物的民族植物学调查

通过对我国热带地区藤黄科(Clusiaceae)植物进行民族植物学调查,了解该科植物的民族植物学传统知识、用途以及资源利用现状,为藤黄科植物资源的合理开发利用和保护提供依据。运用文献研究、实地调查和在关键民族地区进行植物调查等方法,主要记录藤黄科植物的采集地和藤黄科植物的中文名、拉丁名,以及藤黄科植物在原著居民中的当地名和传统用途。对我国热带不同民族地区的藤黄科植物进行整理分类,并对其传统用途进行归纳,使藤黄科植物在少数民族中的食用、药用价值推广开来,推动我国热带民族地区藤黄科植物资源更深层次的开发利用和保护,传承我国少数民族传统文化知识。     

Study of dynamic accumulation of secondary metabolites in three subspecies of Hypericum perforatum

St. John's Wort extracts are used for the treatment of mild to moderately severe depression, and their composition and standardization have been thoroughly investigated. Standardization of St. John's Wort extracts has to cope with several factors that affect the phytochemical profile of the plant, with geographic location, seasonal variations and subspecies all being important. To address this issue, three different subspecies of Hypericum perforatum L. were profiled in relation to different maturation phases, evaluating the variations in the context of the major secondary metabolites from this plant. HPLC analysis indicated that H. perforatum subsp. perforatum is richer in secondary metabolites than the other subspecies, and that the three subspecies show a different profile during the developmental stages. Hypericins, hyperforins and flavonoids peak at quite different stages, and the standardization of Hyperici extracts based only on the contents of hypericin is not adequate to guarantee batch reproducibility of the extracts.     

A new bisxanthone from Hypericum japonicum

A new bisxanthone, named jacarelhyperols D (1), was isolated from the whole plant of Hypericum japonicum. Its chemical structure was elucidated as 6-[1',5',6'-trihydroxy-2'-(alpha-hydroxy-alpha-methyl)ethyl-3',4'-dihydrofuran (2',3',3',4') xanthone-3'-oxyl]-1,3,5-trihydroxy-xanthone on the basis of spectroscopic analysis.     

Antibacterial dihydrobenzopyran and xanthone derivatives from Garcinia cowa stem barks

Two new compounds, garciniacowol (1) and garciniacowone (2) along with 15 known compounds were isolated from the stem barks of Garcinia cowa. Their structures were determined by intensive spectroscopic methods. The structure of 1 was a symmetrical dimeric dihydrobenzopyran derivative, whereas the framework of 2 was a triprenyl caged-xanthone precursor. The antibacterial activities against Escherichia coli TISTR 780, Salmonella typhimurium TISTR 292, Staphylococcus aureus TISTR 1466, and methicillin-resistant S. aureus (MRSA) SK1 of the isolated compounds were also evaluated. Compounds 2 and 9 exhibited good antibacterial activity against MRSA SK1 with the same minimum inhibitory concentration (MIC) value of 2 μg/mL. Moreover, compound 2 also showed good antibacterial activity against S. aureus with an MIC value of 2 μg/mL.     

华南藤黄科植物分类的初步研究

对华南藤黄科植物种类的初步整理和研究，共记载了４属１６种，隶属于３个族，包括华南产３属１２种和外来引种１属４种，其中有１个新种．文章总结了藤黄科器官形态演化趋势，分析了华南藤黄科植物区系的特征及其与邻近地区藤黄科植物区系的关系．     

A new biphenyl and antimicrobial activity of extracts and compounds from Clusia burlemarxii

Phytochemical investigation on Clusia burlemarxii (Clusiaceae) led to isolation and identification of nine compounds. Were isolated from leaves 3-O-α-L- rhamnopyranosylquercetin, 3-O-α-L-rhamnopyranosylkaempferol, 4-hydroxy-5,5-dimethyldihydrofuran-2-one, 2Z-δ-tocotrienoloic acid and friedelin and were isolated from trunk betulinic acid, protocatechuic acid, lyoniresinol, and a new biphenyl 2,2-dimethyl-3,5-dihydroxy-7-(4-hydroxyphenyl)chromane. The structures were determined by ¹H, ¹³C-NMR, DEPT, HMBC, HMQC, HRESIMS. The Minimal Inhibitory Concentration against Streptococcus mutans, Staphylococcus aureus, Bacillus subtilis, Micrococcus luteus, Escherichia coli, Salmonella choleraesuis, Pseudomonas aeruginosa, Aspergillus niger and Cladosporium cladosporioides was also determined. Extracts and compounds showed significant activity against tested Gram-positive bacteria, none activity against tested Gram-negative bacteria and fungi.