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Bon Dr. Jul Rekler 《European Journal of Forest Research》1861,5(1):41-53
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Jer?me?DupuisEmail author Jacques?Badia Marie-Line?Maublanc Richard?Bon 《Journal of Agricultural, Biological & Environmental Statistics》2002,7(2):277-298
We study the influence of age and sex on survival and spatial fidelity of moufl on (Ovis gmelini) in the Caroux-Espinouse massif. Survival and movement probabilities are estimated through a Bayesian analysis of an age-dependent capture-recapture model. Prior information is based on external data, namely on radio-tracked animals. Recapture rates differed between age, sexes, and areas. Whatever the area, survival of males and females less than 5 years old was high and decreased for older animals, particularly males. Female spatial fidelity was high; males were as faithful as females to their capture area in their first 2 years of life but gradually used distinct areas in two successive years as they were getting older. 相似文献
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Effects of garlic powders with varying alliin contents on hepatic drug metabolizing enzymes in rats 总被引:3,自引:0,他引:3
Le Bon AM Vernevaut MF Guenot L Kahane R Auger J Arnault I Haffner T Siess MH 《Journal of agricultural and food chemistry》2003,51(26):7617-7623
The anticarcinogenic effect of garlic has been demonstrated in both epidemiologic and experimental studies. In this study, possible mechanisms involved in the anticarcinogenic effect of garlic consumption were assessed by determining its capacity to alter drug metabolizing enzymes, in relation with its alliin content. Rats were fed a diet for 2 weeks containing 5% garlic powders produced from bulbs grown on soils with different levels of sulfate fertilization and therefore containing differing amounts of alliin. Activities of several hepatic enzymes, which are important in carcinogen metabolism such cytochromes P450 (CYP) and phase II enzymes, were determined. Garlic consumption slightly increased ethoxyresorufin O-deethylase and CYP 1A2 levels. In contrast, garlic consumption decreased CYP 2E1 activity and the level of the corresponding isoform. UDP glucuronosyl transferase and glutathion S-transferase activities were increased by garlic powders. The alliin content of the garlic powders was positively correlated with UGT activity although not with other activities. Effects produced by garlic consumption were qualitatively similar to that of diallyl disulfide, a sulfur compound that has been extensively studied. These data could partially explain the chemoprotective effect of garlic. 相似文献
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Trinh Xuan Hoat Ngo Gia Bon Mai Van Quan Vu Duy Hien Nguyen Duc Thanh Matthew Dickinson 《Phytoparasitica》2012,40(4):351-359
Sugarcane is an important cash crop in Vietnam and has been widely promoted at national and provincial level. In 2006, a new disease was discovered in sugarcane in the Nghean Tate&Lyle Sugar Mill in Nghean Province in north-central Vietnam. The key symptoms were the formation of green grassy shoots around the base of mature stools. We applied nested polymerase chain reaction (PCR) using P1/P7 and R16F2n/R16R2 for detection and characterization of phytoplasma from the symptomatic tissues. PCR products of the expected size (approx. 1200?bp) were obtained from the 16S rDNA of the phytoplasma. The restriction fragment length polymorphism profiles indicated that all samples were infected by the same phytoplasma. Phylogenetic analysis confirmed that the SCGS phytoplasma from Vietnam belong to the 16SrXI group, formerly Rice Yellow Dwarf group. 相似文献
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For years, biochar has been successfully used for the remediation of polycyclic aromatic hydrocarbons(PAHs) in contaminated soils, not only for improving their removal from soil but also for reducing their uptake by crops. However, the underlying mechanism of biochar application reducing PAH uptake and accumulation in winter wheat remains unclear. Pot trials were conducted on a PAH-contaminated soil amended with bamboo biochar, coconut shell biochar,and maize straw biochar(MSB) for an entire gro... 相似文献
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Mathematical modeling and simulation in animal health. Part III: Using nonlinear mixed‐effects to characterize and quantify variability in drug pharmacokinetics
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C. Bon P. L. Toutain D. Concordet R. Gehring T. Martin‐Jimenez J. Smith L. Pelligand M. Martinez T. Whittem J. E. Riviere J. P. Mochel 《Journal of veterinary pharmacology and therapeutics》2018,41(2):171-183
A common feature of human and veterinary pharmacokinetics is the importance of identifying and quantifying the key determinants of between‐patient variability in drug disposition and effects. Some of these attributes are already well known to the field of human pharmacology such as bodyweight, age, or sex, while others are more specific to veterinary medicine, such as species, breed, and social behavior. Identification of these attributes has the potential to allow a better and more tailored use of therapeutic drugs both in companion and food‐producing animals. Nonlinear mixed effects (NLME) have been purposely designed to characterize the sources of variability in drug disposition and response. The NLME approach can be used to explore the impact of population‐associated variables on the relationship between drug administration, systemic exposure, and the levels of drug residues in tissues. The latter, while different from the method used by the US Food and Drug Administration for setting official withdrawal times (WT) can also be beneficial for estimating WT of approved animal drug products when used in an extralabel manner. Finally, NLME can also prove useful to optimize dosing schedules, or to analyze sparse data collected in situations where intensive blood collection is technically challenging, as in small animal species presenting limited blood volume such as poultry and fish. 相似文献
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Bon einem Gr. heff. Dberförfter 《European Journal of Forest Research》1857,1(5):211-214
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Adam R Rivers Michael J Grodowitz Godfrey P Miles Margaret L Allen Brad Elliott Mark Weaver Marie-Claude Bon M Guadalupe Rojas Juan Morales-Ramos 《Journal of insect science (Online)》2022,22(2)
Nezara viridula (L.) (Hemiptera: Pentatomidae), commonly known in the U.S. as the southern green stink bug (SGSB), is a cosmopolitan, highly polyphagous feeder that causes severe damage to a wide range of agronomically important crops such as fruit, vegetable, grain, tobacco, and cotton, throughout much of the United States, and is a global pest of considerable ecological, agricultural, and economical interest. During dissection of female Nz. viridula, conspicuous black and brown spots or lesions were observed on various internal organs. To determine the cause of these spots or lesions, tissues of fat body, spermatheca, ovaries, and ovulated eggs were collected from healthy and infected individuals. The gross morphology of the spots was characterized, and the microorganisms associated with the infection were identified by amplicon sequencing of the V4 region of the small subunit rRNA gene. The presence of a microsporidian pathogen Nosema maddoxi, Becnel, Solter, Hajek, Huang, Sanscrainte, & Estep (Microsporidia: Nosematidae) which has been observed on other species of stink bug, was evidenced for the first time. The characterization of the gross morphology of this associated microsporidian may enable more rapid determination of microsporidia infection in stink bug colonies and field populations. 相似文献