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排序方式: 共有198条查询结果,搜索用时 15 毫秒
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Chalmers GA Nation PN Pritchard J 《The Canadian veterinary journal. La revue veterinaire canadienne》1990,31(4):292-295
Terminal ileitis was diagnosed in three flocks of lambs in different areas of Alberta. Salient clinical features in affected lambs were progressive emaciation with diarrhea, and in some lambs, frequent abdominal stretching. Postmortem findings included thickening of the ileal, and in some animals, the jejunal, cecal and colonic mucosa as a result of mucosal infiltrates of many lymphocytes and fewer plasma cells, eosinophils, globular leukocytes, and neutrophils. Hyperplasia of intestinal lymphoid tissue was prominent in most affected lambs. The cause of the condition is unknown. 相似文献
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AG Loeser Z Shen DS Dessau DS Marshall CH Park P Fournier A Kapitulnik 《Science (New York, N.Y.)》1996,273(5273):325-329
Angle-resolved photoemission experiments reveal evidence of an energy gap in the normal state excitation spectrum of the cuprate superconductor Bi2Sr2CaCu2O8+delta. This gap exists only in underdoped samples and closes around the doping level at which the superconducting transition temperature Tc is a maximum. The momentum dependence and magnitude of the gap closely resemble those of the dx2-y2 gap observed in the superconducting state. This observation is consistent with results from several other experimental techniques, which also indicate the presence of a gap in the normal state. Some possible theoretical explanations for this effect are reviewed. 相似文献
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Genetic diversity within Australian wheat breeding programs based on molecular and pedigree data 总被引:8,自引:0,他引:8
124 wheat cultivars and breeding lines were screened with 19 microsatellite (SSR) loci generating 160 scorable bands which
were used to construct a genetic distance (GD) matrix. A distance matrix based on coefficient of parentage (COP) scores was
also generated for the cultivars for which good pedigree records were available. The SSR and COP data for 101 of the wheat
cultivars were compared with genetic distance scores obtained using1898 scorable restriction fragment length polymorphism
(RFLP) bands previously generated. Phylograms were generated based on the SSR, RFLP,combined SSR and RFLP and COP data. The
standardised Mantel's Z test showed that the distance matrices generated from all of the data sets were significantly correlated.
Bootstrap analysis showed that, although the SSR and RFLP data were correlated, a large number of SSR loci are required for
determining robust genetic relationships between large numbers of cultivars. In addition, accurate pedigree records are needed
to determine genetic relatedness using COP. The molecular data were also used to determine the level of genetic variability
within breeding programs and to assess the impact of the introduction of semidwarf and other germplasm. The results showed
that the level of genetic diversity in Australian wheat cultivars has increased over time and that in particular, the introduction
of semidwarf germplasm resulted in an increase in the overall diversity.
This revised version was published online in August 2006 with corrections to the Cover Date. 相似文献
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Soon FF Ng LM Zhou XE West GM Kovach A Tan MH Suino-Powell KM He Y Xu Y Chalmers MJ Brunzelle JS Zhang H Yang H Jiang H Li J Yong EL Cutler S Zhu JK Griffin PR Melcher K Xu HE 《Science (New York, N.Y.)》2012,335(6064):85-88
Abscisic acid (ABA) is an essential hormone for plants to survive environmental stresses. At the center of the ABA signaling network is a subfamily of type 2C protein phosphatases (PP2Cs), which form exclusive interactions with ABA receptors and subfamily 2 Snfl-related kinase (SnRK2s). Here, we report a SnRK2-PP2C complex structure, which reveals marked similarity in PP2C recognition by SnRK2 and ABA receptors. In the complex, the kinase activation loop docks into the active site of PP2C, while the conserved ABA-sensing tryptophan of PP2C inserts into the kinase catalytic cleft, thus mimicking receptor-PP2C interactions. These structural results provide a simple mechanism that directly couples ABA binding to SnRK2 kinase activation and highlight a new paradigm of kinase-phosphatase regulation through mutual packing of their catalytic sites. 相似文献
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