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排序方式: 共有314条查询结果,搜索用时 15 毫秒
1.
2.
Yuichi Kinoshita Katsuhiko Yoshizawa Yuko Emoto Michiko Yuki Takashi Yuri Nobuaki Shikata Susan A. Elmore Airo Tsubura 《Journal of toxicologic pathology》2016,29(1):53-59
Primary ovarian tumors are generally uncommon in rats used in toxicologic studies. A malignant Sertoli cell tumor was present in the ovary of a 19-week-old female Sprague Dawley rat. Macroscopically, the mass was white and firm, 10 × 13 × 17 mm in size, and located in the right ovary. Histopathologically, the mass was composed of nests of pleomorphic cells, which formed seminiferous-like tubules separated by a thin fibrovascular stroma. The tubules were lined by tumor cells, which had basally located nuclei and abundant eosinophilic and vacuolated cytoplasm. In some areas, the tumor cells were arranged in a retiform growth pattern, mimicking a rete testis/ovarii. Disseminated metastases to the surfaces of the mesentery, spleen and liver were also present. Immunohistochemically, many tumor cells were strongly positive for vimentin, estrogen receptor α and Ki 67. Some tumor cells were positive for pancytokeratin and inhibin α. These findings closely resemble those of an ovarian-derived human malignant Sertoli cell tumor. From our review of the literature, we believe this is the first report of a spontaneous malignant Sertoli cell tumor in the ovary of a young laboratory rat. This case might provide useful historical control information for rat toxicity studies. 相似文献
3.
Robert Manuel L. Juárez-Gómez Juan Chaires-Pacheco Mariana Peña-Ramírez Yuri J. 《New Forests》2020,51(2):335-347
New Forests - Spanish red cedar, Cedrela odorata L. (Meliaceae), is a valuable timber tree in tropical American forests. Existing demand for elite individuals endangers the conservation of... 相似文献
4.
Sugisawa H Itou T Ichimura Y Sakai T 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2002,64(12):1113-1116
Bovine milk contains various immunoreactive components, and the activation of polymorphonuclear leukocytes (PMNLs) function in breast-fed infants has been reported. In this study, the effect of milk on the oxidative burst of bovine PMNLs was investigated in vitro. When PMNLs were incubated with 0.1% colostrum or normal milk, the oxidative burst induced by serum-opsonized Staphylococcus aureus was enhanced, and the enhancement declined dose-dependently. The enhancement of the oxidative burst by milk was not due to opsonins but the priming activities. Also, the phorbol 12-myristate 13-acetate (PMA)-induced oxidative burst increased after incubation with 0.1% colostrum, but the colostral enhancement of the oxidative burst was unaffected by the incubation time. These results suggest that bovine milk contains oxidative burst promoting factor(s). 相似文献
5.
Yuri Zharikov David B. Lank Falk Huettmann Russell W. Bradley Nadine Parker Peggy P. -W. Yen Laura A. Mcfarlane-Tranquilla Fred Cooke 《Landscape Ecology》2006,21(1):107-120
We studied habitat selection and breeding success in marked populations of a protected seabird (family Alcidae), the marbled
murrelet (Brachyramphus marmoratus), in a relatively intact and a heavily logged old-growth forest landscape in south-western Canada. Murrelets used old-growth
fragments either proportionately to their size frequency distribution (intact) or they tended to nest in disproportionately
smaller fragments (logged). Multiple regression modelling showed that murrelet distribution could be explained by proximity
of nests to landscape features producing biotic and abiotic edge effects. Streams, steeper slopes and lower elevations were
selected in both landscapes, probably due to good nesting habitat conditions and easier access to nest sites. In the logged
landscape, the murrelets nested closer to recent clearcuts than would be expected. Proximity to the ocean was favoured in
the intact area. The models of habitat selection had satisfactory discriminatory ability in both landscapes. Breeding success
(probability of nest survival to the middle of the chick rearing period), inferred from nest attendance patterns by radio-tagged
parents, was modelled in the logged landscape. Survivorship was greater in areas with recent clearcuts and lower in areas
with much regrowth, i.e. it was positively correlated with recent habitat fragmentation. We conclude that marbled murrelets
can successfully breed in old-growth forests fragmented by logging. 相似文献
6.
7.
Serotypes and antimicrobial susceptibility of Pseudomonas aeruginosa strains isolated from diseased dogs 总被引:1,自引:0,他引:1
K Ozaki A Inoue H Atobe E Takahashi S Konishi 《Nippon juigaku zasshi. The Japanese journal of veterinary science》1990,52(2):233-239
Strains of Pseudomonas aeruginosa isolated from diseased dogs in Tokyo area during 1983 through 1986 were serotyped and assayed for antimicrobial susceptibility to obtain an epizootiological aspect of canine P. aeruginosa infection. Major sources of specimens were ear and nasal discharges and urine. The results of O-antigen typing using a monoclonal antibody kit showed that the most predominant serotype was type M. Types G and B were also major serotypes. In a yearly distribution of serotypes, type I was almost limited in 1986, and was isolated mainly from surgical wounds, which showed an episode of nosocomial infection, whereas that of type M or B was dispersed during 4 years from 1983 to 1986. As a result of antimicrobial susceptibility test, most canine strains were considered to be susceptible to 4 drugs, which were commonly used in both human and veterinary clinics, in contrast to human isolates. 相似文献
8.
Jie Liu Rumi Fujita Michiko Sato Kuniyoshi Shimizu Fumiko Konishi Kiyoshi Noda Shoichiro Kumamoto Chie Ueda Hisatoshi Tajiri Shuhei Kaneko Yoshitaro Suimi Ryuichiro Kondo 《Journal of Wood Science》2005,51(2):189-192
The inhibitory effects of 102 methanol extracts of 40 mycelia, 9 culture fluids, and 53 fruiting bodies of 40 strains of Ganoderma lucidum on 5-reductase were investigated. The methanol extract of the fruiting body of each strain was found to show the strongest 5-reductase inhibitory activity among the extracts tested. 相似文献
9.
Tomo’omi Kumagai Koichiro Kuraji Hironori Noguchi Yuri Tanaka Katsunori Tanaka Masakazu Suzuki 《Journal of Forest Research》2001,6(4):257-264
Environmental factors, such as global solar radiation, wind speed, air temperature, humidity, and CO2 concentration, were measured above and within the canopy of a tropical rainforest in Lambir Hills National Park, Sarawak,
Malaysia. Few data concerning the environment of this forest have been reported. Intensive observations were carried out in
1998, 1999, and 2000 with the following results: (1) The fraction of global solar radiation reaching the upper layer of the
canopy varied with global solar radiation above the canopy. Even though the global solar radiation above the canopy fluctuated,
the fraction of that reaching the lower canopy and the ground was constantly approximately 5%. (2) The fraction of wind speed
reaching each layer of the canopy increased with wind speed above the canopy. Little wind was usually present at the lower
canopy. (3) The daytime air temperature at the canopy top was higher than that near the ground. The maximum difference between
the air temperature at the canopy top and that at the ground was about 5°C, and the diurnal temperature ranges at the canopy
top and those at the ground were about 8°C and about 5°C, respectively. The highest daytime water vapor pressure occurred
within the canopy and particularly near the ground. Vertical gradients of water vapor pressure during the day were steep,
probably because of high transpiration. (4) In the 1998 observation the minimum and the maximum CO2 concentrations were 360 ppm in the day and 450 ppm at night, while in the 2000 observation the minimum and the maximum CO2 concentrations were 350 ppm in the day and 540 ppm at night. The higher CO2 concentration in the daytime and the lower concentration at night observed during the 1998 observation period were probably
due to reduced photosynthesis and soil respiration caused by exceptional dry conditions during the observation period. 相似文献
10.
S. Poapolathep N. Klangkaew P. Arreesrisom S. Isariyodom Y. Sugita‐Konishi S. Kumagai A. Poapolathep 《Journal of veterinary pharmacology and therapeutics》2015,38(1):101-104
The objective of this study was to investigate the toxicokinetic characteristics of melamine in broilers due to the limited information available for livestock. Melamine was then administered to broiler chickens at an intravenous (i.v.) or oral (p.o.) dosage of 5.5 mg/kg of body weight, and plasma samples were collected up to 48 h. The concentration of melamine in each plasma sample was analyzed using liquid chromatography‐tandem mass spectrometry (LC‐MS/MS). Melamine was measurable up to 24 h after i.v. and p.o. administration. A one‐compartment model was developed to describe the toxicokinetics of melamine in broilers. Following i.v. administration, the values for the elimination half‐life (t1/2β), the volume of distribution (Vd), and the clearance (CL) were 4.42 ± 1.02 h, 00.52 ± 0.18 L/kg, and 0.08 ± 0.01 L/h/kg, respectively. The absolute oral bioavailability (F) was 95.63 ± 3.54%. The results suggest that most of the administered melamine is favorably absorbed from the alimentary tract and rapidly cleared by the kidneys in broiler chickens. 相似文献