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Takumi KOMIYA Akihiro MORI Naohito NISHII Hitomi ODA Eri ONOZAWA Seri SEKI Toshinori SAKO 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(4):661
A 5-year-old castrated male domestic shorthair cat was diagnosed with diabetic ketoacidosis and severe insulin resistance. Although the conventional treatment for diabetic ketoacidosis was provided, the cat required frequent hospitalization because of severe dehydration and repeated diabetic ketoacidosis. We detected anti-insulin antibodies for human in this cat. Serum insulin-binding IgG levels were markedly elevated compared with those in healthy cats and other diabetic cats. We initiated prednisolone to suppress the effects of anti-insulin antibodies. After initiation of prednisolone, the cat was gradually recovered with increasing activity and appetite. Furthermore, satisfactory glycemic control was achieved with combined subcutaneous injection of insulin detemir and insulin degludec. 相似文献
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Sakamaki K Ishizaki S Ohkubo Y Tateno Y Fujita A 《Journal of agricultural and food chemistry》2011,59(12):6667-6671
A test apple beverage made up of apple juice (20%), high-fructose corn syrup (11.5%), citric acid (0.43%), trisodium citrate (0.02%), apple-odor flavor (0.1%), and ascorbic acid (0.02%) was stored at 40 °C and then analyzed for the change of odor in the beverage. Although no thermoacidophilic bacteria (TAB) were detected, a medicinal off-flavor was perceived after the 8 weeks of storage. Model experiments on the ingredients of the test apple beverage revealed that the off-flavor compound had been formed by ascorbic acid and (E)-hex-2-enal. Synthesis and NMR (1H, 13C, HMQC, and HMBC) analyses identified the compound as 6-propylbenzofuran-7-ol. The odor quality, retention index (RI), and mass spectrum of synthetic 6-propylbenzofuran-7-ol were identical with those of the medicinal odor compound from the test apple beverage. Sensory evaluation revealed the recognition thresholds for medicinal odor were 31.4 ppb in water and 24.0 ppb in apple beverage, and the detection thresholds were 19.6 ppb in water and 8.6 ppb in apple beverage, respectively. The quantified concentration of 6-propylbenzofuran-7-ol formed in test apple beverage was 90 ppb, approximately. This concentration was well above the odor threshold, so it was concluded that the compound was the source of the medicinal off-flavor. 相似文献
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Paddy fields converted into winter wheat fields in Hokkaido, Japan, receive extremely high snowfall, creating a risk of flood damage to crops in spring due to waterlogging of snowmelt runoff and poor drainage. Meanwhile, in June there is relatively little rainfall, and a lack of moisture inhibits winter wheat growth. Therefore, we developed a method involving a series of 30-cm-deep ditches in agricultural fields to be used for drainage during the flood-prone period and for furrow irrigation during the dry period using water drawn from the canals that feed the paddy fields. The ditches are called ‘hybrid ditches’ as they are able to perform both drainage and irrigation functions. In this study, we investigated the optimal construction timing and spacing for hybrid ditches. We also evaluated their ability to improve the drainage and irrigation of winter wheat. We found that the optimal timing for digging hybrid ditches is immediately after sowing, and the inter-ditch spacing for irrigation should be 15 m or less. The hybrid ditches promoted increased soil temperature and healthy development of wheat plants by improving drainage during the flood-prone period. In addition, water was successfully supplied via the hybrid ditches to irrigate the fields in June. Under experimental conditions in which rainfall was excluded, grain yield was 10% higher and percent protein content was more than 1% point greater in the irrigated plot compared with the non-irrigated plot. Grain yield was also observed to increase by 3–29% in demonstration tests conducted at local farms. From these results, we conclude that hybrid ditches are capable of improving the growth and yield of winter wheat by improving drainage and providing irrigation in converted paddy fields in Hokkaido. 相似文献
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Eric G. Mworia Takashi Yoshikawa Naoki Yokotani Tetsuo Fukuda Katsuhiko Suezawa Koichiro Ushijima Ryohei Nakano Yasutaka Kubo 《Postharvest Biology and Technology》2010,55(2):108-113
Ethylene biosynthesis in kiwifruit, Actinidia chinensis ‘Sanuki Gold’ was characterized using propylene, an ethylene analog, and 1-methylcyclopropene (1-MCP), an inhibitor of ethylene perception. In fruit harvested between a young stage (66 days after pollination) (DAP) and an early commercial harvesting stage (143 DAP), 2 days of exposure to propylene were sufficient to initiate ethylene biosynthesis while in fruit harvested at commercial harvesting stage (154 DAP), 4 days of propylene treatment were required. This observation suggests that response of ethylene biosynthesis to propylene treatment in kiwifruit declined with fruit maturity. Propylene treatment resulted in up-regulated expression of AC-ACO1, AC-ACO2, AC-SAM1 and AC-SAM2, prior to the induction of AC-ACS1 and ethylene production, confirming that AC-ACS1 is the rate limiting step in ethylene biosynthesis in kiwifruit. Treatment of fruit with more than 5 μL L?1 of 1-MCP after the induction of ethylene production subsequently suppressed ethylene production and expression of ethylene biosynthesis genes. Treatment of fruit with 1-MCP at harvest followed with propylene treatment delayed the induction of ethylene production and AC-ACS1 expression for 5 days. These observations suggest that in ripening kiwifruit, ethylene biosynthesis is regulated by positive feedback mechanism and that 1-MCP treatment at harvest effectively delays ethylene production by 5 days. 相似文献
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We investigated the validity and efficiency of a survey using sight per unit effort (SPUE) of sika deer and shrub-layer decline
rank (SDR), which is an index of decline in the physical structure of a whole stand caused by sika deer, based on data collected
on a broad scale. This survey was to be used to manage a deer population in order to conserve a forest ecosystem. First, we
evaluated the spatial and temporal scales of deer density that are most appropriate for predicting decline in the status of
understory vegetation. The model with SPUE calculated in a buffer with a radius of 4.5 km using data for the past 4 years
was found to be the best. We showed that our knowledge of the relationship between deer density and status of shrub-layer
vegetation is improved by identifying the most suitable spatial and temporal scales of SPUE for predicting SDR. Next, we quantified
the effects of SPUE and environmental components on SDR in stands. We found that SPUE had the greatest effect on SDR among
all explanatory variables. Moreover, the area under the curve (AUC) was large in a model that only used SPUE (AUC = 0.718).
This result suggests that the variation in SDR among stands was explained well by SPUE regardless of differences in the forest
environment. Furthermore, we identified the effective values of SPUE for preventing shrub-layer vegetation from declining
through deer density control. We conclude that a management system based on SPUE and SDR is a simple and valid method for
managing deer populations in order to conserve forest ecosystems. 相似文献
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Yasutaka Watanabe Rie Mihara Tohru Mitsunaga Tsuyoshi Yoshimura 《Journal of Wood Science》2005,51(5):514-519
Fractions of methanol and ethanol extracts from the heartwood of white cypress pine (Callitris glaucophylla Thompson et Johnson) were investigated for their repellent activity against subterranean termite Coptotermes formosanus Shiraki worker using a two-choice semicircular filter paper test at 0.5% (w/w) concentration. Fraction CY-E2 composed of
(−)-citronellic acid, guaiol, α-, β-, and γ-eudesmol isomers as well as an unknown compound, showed the highest statistically significant repellency (97.8% ± 2.2 SEM)
of all fractions tested. Bioactivity-guided fractionations using high-performance liquid chromatography led to the isolation
of two, oxygenated eudesmane-type sesquiterpenes with α-methylene moieties, both termite-repellent compounds. These compounds were subsequently identified as ilicic acid methyl
ester (IAME) and costic acid by means of spectroscopic analyses, electron impact mass spectrometry, and nuclear magnetic resonance
spectroscopy. We report the isolation of both IAME and costic acid from C. glaucophylla heartwood for the first time.
Part of this paper was presented at the 47th Symposium on the Chemistry of Terpenes, Essential Oils, and Aromatics, Tokyo,
November 2003 相似文献
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Masahiro MIYABE Azusa GIN Eri ONOZAWA Mana DAIMON Hana YAMADA Hitomi ODA Akihiro MORI Yutaka MOMOTA Daigo AZAKAMI Ichiro YAMAMOTO Mariko MOCHIZUKI Toshinori SAKO Katsutoshi TAMURA Katsumi ISHIOKA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(10):1201-1206
G protein-coupled receptor (GPR) 120 is an unsaturated fatty acid receptor, which is
associated with various physiological functions. It is reported that the genetic variant
of GPR120, p.Arg270His, is detected more in obese people, and this genetic variation
functionally relates to obesity in humans. Obesity is a common nutritional disorder also
in dogs, but the genetic factors have not ever been identified in dogs. In this study, we
investigated the molecular structure of canine GPR120 and searched for candidate genetic
variants which may relate to obesity in dogs. Canine GPR120 was highly homologous to those
of other species, and seven transmembrane domains and two N-glycosylation sites were
conserved. GPR120 mRNA was expressed in lung, jejunum, ileum, colon, hypothalamus,
hippocampus, spinal cord, bone marrow, dermis and white adipose tissues in dogs, as those
in mice and humans. Genetic variants of GPR120 were explored in client-owned 141 dogs,
resulting in that 5 synonymous and 4 non-synonymous variants were found. The variant
c.595C>A (p.Pro199Thr) was found in 40 dogs, and the gene frequency was significantly
higher in dogs with higher body condition scores, i.e. 0.320 in BCS4–5 dogs, 0.175 in BCS3
dogs and 0.000 in BCS2 dogs. We conclude that c.595C>A (p.Pro199Thr) is a candidate
variant relating to obesity, which may be helpful for nutritional management of dogs. 相似文献
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Possible degradation of type I collagen in relation to yellowtail muscle softening during chilled storage 总被引:1,自引:0,他引:1
ABSTRACT: In this paper, the detection of type I collagen degradation during the softening phenomenon of yellowtail muscle, was examined. Acid soluble collagen was isolated from dorsal ordinary muscle at death and after 24-h chilled storage. In the abundant ratio of subunit components, an increase in β12 chain (5.4 points) and a decrease in components with molecular weights larger than γ chain (7.0 points) after 24-h chilled storage, was found. Type I collagen was detected in the alkali-soluble fraction by SDS-PAGE. Its amount calculated from hydroxyproline contents in alkali-soluble fraction was increased from 0.097 mg/g muscle to 0.155 mg/g muscle during 24-h storage. The increased alkali-soluble collagen (0.058 mg/g muscle) was about 1.4% of whole collagen. These results suggest that a slight decomposition of type I collagen of yellowtail muscle may occur and subsequently becomes alkali-soluble corresponding to postmortem softening. 相似文献