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1.
In mid-September, 1 month before the insertion of intravaginal pessaries to induce sexual activity, blood samples were collected every 4 days from 16 ewe lambs aged 7 months, in order to determine the incidence of ovulations by measurement of plasma progesterone concentrations. It has been studied whether the response to a progestagen treatment of ewe lambs apparently close to puberty could be modified by the onset of the ovarian events preceding puberty. The effect of the presence or absence of ovulations prior to progestagen treatment on the potential reproductive performance (fertility, litter size and fecundity), embryo development [embryo quality and interferon-tau (IFNτ) secretion], luteal function (progesterone secretion in vitro ) and endometrial progesterone content was studied in seven ovulating (Ov+) and nine nonovulating ewe lambs (Ov−) on day 14 after mating. The best potential reproductive results were obtained with Ov+ animals, although these differences could not be initially attributed to either different progesterone secretion in vitro or concentration of endometrial progesterone. Irrespective of the experimental groups, secretion of progesterone by luteal tissue from ewe lambs with normal embryos was significantly greater (p<0.05) than that of animals with abnormal embryos or with no embryos. Normal embryos secreted a higher amount of IFN-τ than those embryos classified as abnormal (p<0.07). In conclusion, ewe lambs which exhibit luteal activity before puberty have the highest levels of reproductive performances after a progestagen treatment. Corpora lutea from ewe lambs with normal embryos had higher rates of progesterone secretion in vitro and their embryos had a higher IFN-τ production by the embryos, indicating greater capacity for subsequent development. 相似文献
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K. A. Selting S. E. Lana G. K. Ogilvie A. Olmstead D. L. Mykles J. Bright K. L. Richardson J. A. Walton E. Monnet M. J. Fettman 《Veterinary and comparative oncology》2004,2(3):142-156
The cumulative cardiotoxicity that occurs as a result of doxorubicin chemotherapy is irreversible and can affect both quality and quantity of life for the cancer patient. Cardiac troponin I (cTnI) is a sensitive and specific marker of cardiomyocyte death. The purpose of this retrospective study was to evaluate serum concentrations of cTnI in dogs with lymphoma or osteosarcoma given doxorubicin chemotherapy, and with known cardiac outcome, based on a minimum assessment by physical examination and thoracic radiography. Serum samples were also available for cTnI measurement from seven healthy dogs given intracoronary doxorubicin. Serial serum samples obtained before, during and after doxorubicin chemotherapy showed increased cTnI concentrations in some clinical patients following chemotherapy (P = 0.0083 compared to baseline), but this did not correlate with clinical signs of cardiomyopathy. In dogs that subsequently developed cardiomyopathy however, serum cTnI concentrations were elevated before clinical signs became evident (confirmed with echocardiography). 相似文献
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Objective To establish the prevalence of intussusceptions involving the caecum in a population of horses admitted to a university hospital for colic. Design Retrospective clinical study Methods Medical records of all horses admitted to the Massey University Veterinary Teaching Hospital between 1991 and 2004 were examined for information of those horses diagnosed with an intussusception involving the caecum. Results A total of 135 horses were admitted for colic surgery during the study period and 61 horses had a diagnosis of ileocaecal (37), caecocaecal (5) or caecocolic intussusception (19) made either at surgery or necropsy. Of the horses with ileocaecal intussusception, 32 had an incomplete hand-sewn ileocaecostomy without reduction and 29 survived to discharge. All the horses with caecocaecal intussusceptions were diagnosed preoperatively via rectal examination and/or transabdominal ultrasound: 2 were euthanased at surgery and 3 survived to discharge. In the 19 horses with caecocolic intussusceptions, manually reduction at surgery was performed in 6 and 5 of them survived to discharge. A typhlectomy was performed via a colotomy in 6 horses, 3 of which survived to discharge. Conclusions The high prevalence of intussusceptions involving the caecum seen at this referral centre may indicate a higher prevalence in New Zealand than is reported elsewhere in the world. Clinical relevance Intussusceptions involving the caecum should be considered as a differential diagnosis in horses presenting with chronic low-grade colic. Transabdominal ultrasound is useful for identifying caecocaecal and caecocolic intussusceptions. Hand-sewn side-to-side incomplete ileocaecostomy is a quick, effective and safe method of surgical treatment of ileocaecal intussusceptions. 相似文献
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Virginia Buechner-Maxwell Mark Crisman Michael Murray William Ley Geoffrey Saunders Amelia Walton 《Journal of Equine Veterinary Science》1996,16(9):375-379
Transtracheal wash and bronchoalveolar lavage are diagnostic techniques that have been adopted from human medicine for monitoring inflammatory changes in the airway of the horse. Transendoscopic biopsy has also proven to be a valuable tool for obtaining samples of the airway mucosa in human patients. A transendoscopic technique was developed in this study for obtaining a respiratory mucosal biopsy from standing, sedated horses. Six normal adult horses were sampled at eight-week intervals for a total of three sample periods. Horses were monitored for adverse effects of the technique and none were noted. Sample sites were completely healed after eight weeks with no gross or histologic abnormalities. Biopsy samples were 3 to 4 millimeters in diameter, and 17 of 18 samples provided interpretable histological sections. Methods for handling, staining and evaluating tissue were also developed. The results of this study demonstrated that airway mucosal biopsy is a safe, repeatable technique that can be performed in the sedated, standing horse. 相似文献
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C.B. Cowey J.W. Adron R. Hardy J.G.M. Smith M.J. Walton 《Aquaculture (Amsterdam, Netherlands)》1979,16(3):199-209
Three groups of rainbow trout were given diets containing different amounts (12–36%) of collagenous by-product derived from partially rendered hide fleshings still containing an appreciable amount of saturated fat. A fourth group of trout were given a control diet containing as protein source a fish protein concentrate, and, as a source of essential fatty acids, a marine oil. The diets were fed for 12 weeks, hide fleshings replacing part of the marine oil and fish protein concentrate in the three test diets. Weight gains and protein utilization of the four groups of rainbow trout were all similar with all four diet treatments. No adverse effects on the fish were observed from the use of hard fat, although an increase in the concentration of some monounsaturated fatty acids occurred in tissues of those fish given hide fleshings. Tests of mitochondrial function gave normal values for both control and test fish. Organoleptic tests demonstrated that trout given diets containing hide fleshings were not distinguishable from normal trout. The results show that provided nutritional requirements are met (especially in the present instance with respect to essential amino acids and essential fatty acids) this by-product can form a useful component in trout rations. 相似文献
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The effects of dietary flax oil and antioxidants on ascites and pulmonary hypertension in broilers using a low temperature model 总被引:4,自引:1,他引:3
1. Three experiments were conducted using a low temperature model to induce pulmonary hypertension (PH) and ascites in broiler chickens. Diets containing 25 g or 50 g flax oil/kg food and control diets with an equivalent amount of animal/vegetable (A/V) blend oil, with and without supplemental antioxidants (vitamin C and vitamin E) were used. The amount of PH was assessed by the ratio of right ventricle weight to total ventricle weight (RV/TV ratio). Birds were considered to suffer from pulmonary hypertension syndrome (PHS) if the RV/TV ratio was greater than 0.299. 2. In experiment 1, the test diets contained 50 g oil/kg food and were given during the grower period only. Birds fed on the flax oil diet tended to have a lower incidence of PHS, ascites and lower RV/TV ratios than birds fed on the control diet. However, when the flax oil diet was supplemented with antioxidants, the incidence of ascites, PHS, haematocrit and whole blood and plasma viscosity increased compared with birds fed on the flax oil diet without antioxidants. These effects were not seen in experiment 2, when the test diets containing 30 g oil/kg food (25 g flax oil plus 5 g A/V blend oil/kg food compared to 30 g A/V blend oil/kg food) were given during the grower period. However, in experiment 3, when the test diets containing 30 g oil/kg food were given from day 1 to week 8, birds fed on the control diet supplemented with antioxidants had a higher incidence of PHS than those fed on the control diet alone. 3. In all 3 experiments, there was no significant effect of dietary fat source or supplemental antioxidants on total food intake or food conversion. 4. We conclude that diets containing 50 g flax oil/kg food tend to reduce the incidence of PHS and ascites in broilers using a low temperature model but the results were not statistically significant. In some cases, supplementing diets with a combination of vitamin E and vitamin C increased the incidence of ascites and PHS. 相似文献
9.
J S Walton 《Journal of animal science》1986,62(1):9-15
Two hundred sixty-two sows were used to investigate the effects of boar exposure during the last week of nursing (BPRE) and after weaning (BPOST) on the return to estrus. Because approximately one-half of the sows were weaning their first litter, a third factor, primiparous vs multiparous (LITT), was considered in the statistical analysis. To evaluate the effect of treatment on ovarian activity, the sows were also blood-sampled twice weekly for 3 wk after weaning for the measurement of plasma progesterone concentrations as an index of ovulation. Boar exposure after weaning was the most important stimulus of early ovulation and estrus after weaning (P less than .001). A greater proportion of first-litter sows exhibited estrus later (P less than .02) and ovulated later (P less than .09) than did multiparous sows. First-litter sows were unaffected (P greater than .10) by boar exposure before weaning. Multiparous sows were sensitive to boar exposure during nursing. Maximal boar exposure for these sows (BPRE + BPOST) resulted in 95% of sows in estrus and ovulating within 20 d of weaning. No boar exposure resulted in 45% and 38% anestrus and anovulatory sows. Boar exposure, either before or after weaning, was effective in reducing the number of anestrus and anovulatory sows to between 15 to 30%. The effects of BPRE and BPOST on return to ovulation were additive and approximately equal. 相似文献
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