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卵泡从原始卵泡发育为成熟卵泡,直至排卵、黄体发育等过程都受到精密的调控,产生大量的优势卵泡是绵羊产多羔及实现快速扩繁的关键因素。研究发现,相关信号通路和转录因子通过影响绵羊卵泡中卵母细胞、颗粒细胞的生长,进而调控卵泡的发育成熟,对这些信号通路进行深入了解,有助于探索卵泡发育的调控机制,早日实现绵羊高效繁育。Notch是卵泡发育过程中发挥重要作用的高度保守信号通路,PI3K/AKT/mTOR信号通路各成员都是广泛存在于细胞内的信号转导分子,在卵泡发育早期发挥了主要作用,还有间隙连接(gap junction,GJ)和跨带突触(transzonal projections,TZPs)等物理连接方式,在细胞间的交流通讯起到重要作用。作者详细介绍了Notch信号通路、PI3K/AKT/mTOR信号通路、间隙连接及跨带突触的结构功能在绵羊卵泡发育中的调控作用,为进一步探明绵羊卵泡发育的调控机制提供参考。 相似文献
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Hilton C Diniz Neto Mayara C Lombardi Mariana M Campos Andrey P Lage Rodrigo O S Silva Elaine Maria Seles Dorneles Camila Flvia A Lage Wanessa A Carvalho Fernanda S Machado Luiz Gustavo R Pereira Thierry R Tomich Carolina P Ramos Ronnie A Assis Francisco Carlos F Lobato Jordana A Santana Ethiene Luiza S Santos Rafaella S Andrade Sandra G Coelho 《Journal of animal science》2021,99(5)
The aim of this study was to identify possible effects of different vaccination strategies (concomitantly or not) against brucellosis and clostridia on intake, performance, feeding behavior, blood parameters, and immune responses of dairy heifers calves. Fifty heifers calves were enrolled [38 Gyr (Zebu, Bos taurus indicus) and 12 5/8 Holstein Gyr]. At 120 d of age, animals were randomly distributed among 3 groups: B (n = 18), vaccinated against brucellosis; C (n = 14), vaccinated against clostridia and CB (n = 18), vaccinated concomitantly for both. Rectal and thermographic temperatures were evaluated on days 1, 0, 1, 2, 3, 5, 7,10, 14, and 28 relatives to the vaccination day. Feed and water intake, body weight (BW), and feeding behavior were monitored daily by an electronic feeding system. Blood was sampled on days 0, 3, 7, 14, and 28, relative to the vaccination day for determination of glucose and -hydroxybutyrate (BHBA) concentrations. Blood sampled on day 0 (prevaccination) and on days 28 and 42 were used to evaluate the immune response against Brucella abortus and clostridia. There was an increase in rectal temperature between the first and the third day postvaccination in the 3 groups. The thermography revealed an increase of local temperature for 7 d on groups B and CB. Group C had increased local temperature for a longer period, lasting for up to 14 d. Dry mater intake was reduced for groups B and CB, but no alteration was observed for group C. No alterations regarding initial BW, final BW, average daily weight gain, and feed efficiency were observed. No differences were observed for the 3 vaccination groups for blood parameters throughout the evaluation period. The concomitant vaccination against brucellosis and clostridia led to lower neutralizing antibody titers against epsilon toxin of Clostridium perfringens and botulinum toxin type C of C. botulinum (C > CB > B). When cellular proliferation assay and serological tests to B. abortus were evaluated, no differences were observed between groups B and CB. The present results indicate that the concomitant vaccination against brucellosis and clostridia has no relevant impact on the intake, performance, and feeding behavior of dairy calves. However, the concomitant vaccination of vaccines against these 2 pathogens impacts animal immunity against clostridial infections. 相似文献
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卫星降水产品在缺资料地区开展水文气象研究及径流模拟中发挥着至关重要的作用,然而卫星降水产品的精度可能会影响径流模拟效果。采用多种统计指标和VIC水文模型综合评估5种卫星降水产品(CMORPH-BLD、GSMaP_Gauge、CMFD、MSWEP和PERSIANN-CDR)在雅鲁藏布江流域的精度和拉萨河流域的水文模拟效果。结果表明:(1)CMORPH_BLD和GSMaP_Gauge在少雨季存在低估,CMFD在少雨季与观测值具有很好的一致性。MSWEP和PERSIANN-CDR在多雨季和少雨季存在高估。降水量方面,CMORPH-BLD和CMFD均较为接近观测值,其他降水产品存在不同程度的高估。(2)日尺度上,除CMFD外其他卫星降水数据与观测值具有较小的相关性(0.26~0.45),CMORPH-BLD和CMFD和观测值具有较好的一致性,CMFD和MSWEP探测小降水事件(0.1,0.5,1 mm/d)的能力优于GSMaP_Gauge。各卫星降水产品在探测强降水(2,5,10 mm/d)方面能力不足。日降水2 mm/d的降水阈值为各分类指数的变化点。(3)月尺度上,各降水产品与观测值具有很... 相似文献
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A. M. PIRES M. F. MAGALHÃES L. MOREIRA DA COSTA M. J. ALVES & M. M. COELHO 《Fisheries Management and Ecology》2008,15(1):49-58
Abstract The effects of an extreme flash flood on the native fish assemblages across a Mediterranean catchment in Southwest Portugal were investigated. The fish community structure and habitat were surveyed at 10 sites pre- and post-flood. Overall species richness and rank abundances changed little after the flood, despite there being a consistent decline in the abundance of small cyprinids. Pre- and post-flood habitat correlates of abundance changed for at least some species, and variability in assemblage structure was associated with flood, depth and pH. These results indicate that extreme floods occurring early in the wet season may have little disruptive effects on the overall structure of native fish assemblages in Mediterranean streams, although may at least partially influence population dynamics for some species. Habitat quality and complexity are likely to play a role in mediating species responses to flooding. 相似文献
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森林生物量测定一直是森林生态系统研究的主要内容,也是地区森林生态系统长期监测所必需的基础性研究。以浙江天童国家森林公园常绿阔叶林为研究对象,于2003年10月份采用收获法(草本层、灌木层)和标准木法(乔木层)相结合的方法,测定了以木荷Schimasuperba,米槠Castanopsis carlesii为优势种的群落地上部分生物量。结果表明:群落地上部分总生物量为(141.0770±17.4298)t.hm-2(平均值±标准差,n=3),其中接近90%集中于乔木层,其他层生物量分配较少。群落及其各层生物量种间分配差异较大,以优势树种木荷和米槠生物量为主,其生物量主要由树干组成,器官分配大小顺序为干>枝>叶。群落萌枝生物量主要集中在灌木层,50%以上由米槠萌枝生物量构成。群落生物量及其分配状况基本体现了以木荷和米槠为优势种的该群落结构特征及常绿阔叶林群落生物量分配特征。表5参15 相似文献