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Sixty clinically normal German shepherd dogs, 31 males and 29 females, ranging in age from 1 and 5 years and with a body weight ranging from 22 to 37.2 kg, were examined by the two-dimensional mode, M-mode, and Doppler echocardiography. In Doppler mode, the mitral valve flows were obtained, where the aim was to determine the velocity peaks and ratios of the E and A waves and the mitral E wave deceleration time. The velocity peaks were obtained for the tricuspid, pulmonary and aortic valves. On the left ventricular outflow tract flow, the time velocity integral and aortic cross-sectional area was used to calculate the cardiac output. A statistically significant correlation with the body weight was found for the systolic left atrial and diastolic aortic diameter on two-dimensional mode. On M-mode, there was a significant correlation between the body weight and the systolic left atrium and diastolic aortic dimension, systolic and diastolic left ventricular, septal and posterior wall dimensions. Doppler echocardiography showed that there was no significant correlation between the body weight and the mitral, tricuspid, pulmonary and aortic valves flows. These results demonstrate that it is important to know the normal echocardiographic values for German shepherd dogs because there are some characteristics peculiar to this particular breed. The data obtained is expected to be helpful for studies on small animal cardiology.  相似文献   
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According to a study conducted on a population of 9,248 subjects, cardiac diseases are the second most prevalent cause of death in the dog. During the last decades, a common scenario has been the increase on life expectancy of dogs. The exact relationship between the negative modifications of cardiovascular function and the development of specific cardiovascular diseases is difficult to ascertain, and also, the effect of age per se on vascular impedance is important. It may result in limited cardiovascular reserve under conditions of increase demand in senescent animals. To evaluate the effect of age on the peripheral vasculature specifically, the objective of this study was to compare parameters of the regional blood flow as well as compliance and resistance indexes in the femoral arterial system of younger and older conscious healthy dogs by duplex Doppler ultrasonography. The data were collected from 16 mixed-breed dogs divided into two groups: young and old healthy dogs. In all dogs Doppler spectra blood flow patterns of the femoral artery were triphasic. Significant differences were not found between the parameters measured for young and old groups. Despite this, the average value of femoral flow volume in the older group was approximately 50% lower than the younger group. This finding could play an important role in limiting exercise response with age. In order to validate these speculations, further studies should be performed in aged dogs.  相似文献   
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