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排序方式: 共有159条查询结果,搜索用时 15 毫秒
1.
Lactate Kinetics in veterinary Critical Care: A Review 总被引:3,自引:0,他引:3
Michael S. Lagutchik DVM Gregory K. Ogilvie DVM Wayne E. Wingfield MS DVM Timothy B. Hackett DVM MS 《Journal of Veterinary Emergency and Critical Care》1996,6(2):81-95.
Elevation in blood lactate concentration, with or without accompanying metabolic acidosis, is a hallmark finding in patients with circulatory compromise, and is also consistently noted in other conditions affecting critically ill or injured individuals. Little is reported in a veterinary literature regarding lactate measurement in the emergency and critical care setting, despite impressive reports of the clinical usefulness of lactate measurement in people. The purpose of this article is to review lactate kinetics and the clinical utility of lactate measurement. Limitations to lactate evaluation will also be discussed. 相似文献
2.
Anthony S. Moore BVSc MVSc Gregory K. Ogilvie David M. Vail 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1994,8(5):343-344
Twenty-five dogs with malignant lymphoma refractory to chemotherapy were treated with actinomycin D at a median dose of 0.7 mg/m2 (range, 0.5 to 0.9 mg/m2 ) every 3 weeks. The dogs treated had received between 2 and 8 chemotherapeutic agents (median 7), for a median of 266 days before being treated with actinomycin D. For 23 of the 25 dogs, previous chemotherapy included doxorubicin. No dog responded to actinomycin D chemotherapy. 相似文献
3.
Phillip F. Steyn BVSc MRCVS MS Gregory Ogilvie DVM 《Veterinary radiology & ultrasound》1995,36(2):160-163
Technetium-99m methoxy-isobutyl-isonitrile (sestamibi) is a radiophartnaceutical used for the evaluation of myocardial perfusion. Increased uptake of sestamibi has also been documented in tumors. The objective of this study was to document the extracardiac biodistribution of 99m Tc sestamibi in the normal dog. Nine normal beagles were given 0.35 mCi/kg 99m Tc sestamibi intravenously, and 60 second images were made of the entire body at 1 hour post injection. A defined distribution pattern was recognized, with good visualization of the heart, liver, gallbladder, small intestine, kidneys, urinary bladder, popliteal lymph nodes, parotid salivary glands and zygomatic salivary glands. Splenic uptake was not seen.
Target to background ratios were calculated for all the regions listed, using background regions-of-interest with the smallest coefficient of variance for the denominator. The mean, range and standard deviation of these ratios are given. 相似文献
Target to background ratios were calculated for all the regions listed, using background regions-of-interest with the smallest coefficient of variance for the denominator. The mean, range and standard deviation of these ratios are given. 相似文献
4.
Keane DP Horney FD Ogilvie TH 《The Canadian veterinary journal. La revue veterinaire canadienne》1983,24(2):57-59
A four day old Holstein calf was presented with a history of recurrent free gas bloat. An exploratory laparotomy was performed and no abnormalities were discovered in the gastrointestinal tract. An esophagotracheal fistula was suspected and confirmed by endoscopy. Surgical correction was performed by ligating the tubular connection between the trachea and esophagus and suturing closed the defects in these structures. 相似文献
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K. A. Selting S. E. Lana G. K. Ogilvie A. Olmstead D. L. Mykles J. Bright K. L. Richardson J. A. Walton E. Monnet M. J. Fettman 《Veterinary and comparative oncology》2004,2(3):142-156
The cumulative cardiotoxicity that occurs as a result of doxorubicin chemotherapy is irreversible and can affect both quality and quantity of life for the cancer patient. Cardiac troponin I (cTnI) is a sensitive and specific marker of cardiomyocyte death. The purpose of this retrospective study was to evaluate serum concentrations of cTnI in dogs with lymphoma or osteosarcoma given doxorubicin chemotherapy, and with known cardiac outcome, based on a minimum assessment by physical examination and thoracic radiography. Serum samples were also available for cTnI measurement from seven healthy dogs given intracoronary doxorubicin. Serial serum samples obtained before, during and after doxorubicin chemotherapy showed increased cTnI concentrations in some clinical patients following chemotherapy (P = 0.0083 compared to baseline), but this did not correlate with clinical signs of cardiomyopathy. In dogs that subsequently developed cardiomyopathy however, serum cTnI concentrations were elevated before clinical signs became evident (confirmed with echocardiography). 相似文献
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9.
Hammer A Getzy D Ogilvie G Upton M Klausner J Kisseberth WC 《Journal of the American Animal Hospital Association》2001,37(5):478-482
Twenty-four dogs and 30 cats with histopathologically confirmed salivary gland neoplasia were retrospectively reviewed in a multi-institutional study. The predominant presenting complaint for animals with salivary gland neoplasia was that of a mass being noted by the owner; other common complaints included halitosis, dysphagia, and exophthalmia. Siamese cats were overrepresented, indicating a possible breed predisposition. The most common histopathological type was simple adenocarcinoma. Cats had more advanced disease at diagnosis than did dogs, and clinical staging was prognostic in dogs. The median survival times for dogs and cats were 550 days and 516 days, respectively. 相似文献
10.
Jankowski MK Ogilvie GK Lana SE Fettman MJ Hansen RA Powers BE Mitchener KM Lovett SD Richardson KL Parsley L Walton JA 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2002,16(1):105-108
Matrix metalloproteinases (MMPs) are enzymes that play key roles in angiogenesis, tumor invasion, and metastasis in a wide variety of species. The purpose of this study was to evaluate pro and active MMP 2 and 9 concentrations in tumor, normal stromal tissue, and serum from tumor-bearing cats. We hypothesized that serum concentrations of pro and active forms of MMPs 2 and 9 would be predictive of MMP concentrations in tumor tissue and that these MMP concentrations would correlate with the histopathologic grade of the malignancies. Pro and active forms of MMPs 2 and 9 were determined by gelatin zymography and subsequent computerized densitometry from tumor and nearby stromal tissue and serum from 49 cats with various malignancies. The serum concentrations of MMPs from these tumor-bearing cats were compared with serum concentrations of MMPs from 44 normal cats of similar age and gender. Measurable concentrations of MMPs 2 and 9 were found within tumor, stromal, and serum samples. Mean concentrations of total pro and active MMPs 2 and 9 within tumor tissue were significantly higher (P values <.0001, .0031, <.001, and .0064, respectively) when compared with stromal tissue from the same animals. Serum MMP concentrations from tumor-bearing cats were higher than those from normal cats. Poor correlation was found between serum MMP concentrations and tissue MMP concentrations of increasing histologic grades of malignancies. 相似文献