排序方式: 共有14条查询结果,搜索用时 246 毫秒
1.
2.
Biological control of chestnut blight in Croatia: an interaction between host sweet chestnut,its pathogen Cryphonectria parasitica and the biocontrol agent Cryphonectria hypovirus 1
下载免费PDF全文
![点击此处可从《Pest management science》网站下载免费的PDF全文](/ch/ext_images/free.gif)
3.
4.
Ronald Gwatkin Lucia Dzenis A. S. Greig C. Grinewitsch 《Canadian journal of veterinary research》1954,18(10):341-346
5.
6.
7.
Journal of Soils and Sediments - We conducted this investigation in order to develop a simple method for the determination of bioavailable vanadium and its speciation within sediments. The... 相似文献
8.
Dzenis Y 《Science (New York, N.Y.)》2008,319(5862):419-420
9.
Nace Zidar Sofia Montalv?o ?iga Hodnik Dorota A. Nawrot Ale? ?ula Janez Ila? Danijel Kikelj P?ivi Tammela Lucija Peterlin Ma?i? 《Marine drugs》2014,12(2):940-963
Marine organisms produce secondary metabolites that may be valuable for the development of novel drug leads as such and can also provide structural scaffolds for the design and synthesis of novel bioactive compounds. The marine alkaloids, clathrodin and oroidin, which were originally isolated from sponges of the genus, Agelas, were prepared and evaluated for their antimicrobial activity against three bacterial strains (Enterococcus faecalis, Staphylococcus
aureus and Escherichia
coli) and one fungal strain (Candida albicans), and oroidin was found to possess promising Gram-positive antibacterial activity. Using oroidin as a scaffold, 34 new analogues were designed, prepared and screened for their antimicrobial properties. Of these compounds, 12 exhibited >80% inhibition of the growth of at least one microorganism at a concentration of 50 µM. The most active derivative was found to be 4-phenyl-2-aminoimidazole 6h, which exhibited MIC90 (minimum inhibitory concentration) values of 12.5 µM against the Gram-positive bacteria and 50 µM against E. coli. The selectivity index between S. aureus and mammalian cells, which is important to consider in the evaluation of a compound’s potential as an antimicrobial lead, was found to be 2.9 for compound 6h. 相似文献
10.