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E Gwinner 《Science (New York, N.Y.)》1974,185(4145):72-74
Under the influence of testosterone, the free-running circadian rhythm of locomotor activity of the starling, Sturnus vulgaris, tends to "split" into two components which temporarily run with different circadian frequencies: "splitting" occurred in intact birds whose testes grew, and in castrated birds that were injected with testosterone. Since "splitting" most probably reflects the temporal separation of two (or two groups of) circadian oscillators, these results suggest that testosterone affects the mutual coupling of circadian oscillators controlling locomotor activity. 相似文献
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Like other tropical birds, African stonechats breeding at the equator reproduce once a year during the main rainy season and subsequently carry out a complete molt. These two activities are controlled by endogenous circannual mechanisms: in stonechats held in constant conditions of photoperiod and temperature, a rhythm of gonadal size and molt persisted for up to 7.5 years, which would be a lifetime for free-living conspecifics. The fact that the period of these rhythms deviated from 12 months demonstrates their true endogenous nature. The results represent the longest circannual reproductive rhythm yet documented and suggest that circannual mechanisms may be of particular importance for reproductive timing in tropical organisms. 相似文献
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The future demand for and potential shortages of food-supply veterinarians have been the subject of much concern. Using the Delphi forecasting method in a three-phase Web-based survey process, a panel of experts identified the trends and issues shaping the demand for and supply of academic food-animal veterinarians, then forecasted the likely future demand and shortages of food-supply veterinarians employed in academic institutions in the United States and Canada through 2016. The results indicate that there will be increasing future demand and persistent shortages of academic food-supply veterinarians unless current trends are countered with targeted, strategic action. The Delphi panel also evaluated the effectiveness of several strategies for reversing current trends and increasing the number of food-supply veterinarians entering into academic careers. Academic food-supply veterinarians are a key link in the system that produces food-supply veterinarians for all sectors (private practice, government service, etc.); shortages in the academic sector will amplify shortages wherever food-supply veterinarians are needed. Even fairly small shortages have significant public-health, food-safety, animal-welfare, and bio-security implications. Recent events demonstrate that in an increasingly interconnected global economic food supply system, national economies and public health are at risk unless an adequate supply of appropriately trained food-supply veterinarians is available to counter a wide variety of threats ranging from animal and zoonotic diseases to bioterrorism. 相似文献
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G Elamaran KP Singh MK Singh SK Singla MS Chauhan RS Manik P Palta 《Reproduction in domestic animals》2012,47(6):1027-1036
This study examined the effects of O2 concentration (5% vs 20%) during in vitro maturation (IVM), fertilization (IVF) and culture (IVC) or supplementation of IVM and IVC media with cysteamine (50 and 100 μm , respectively; IVM, IVF and IVC carried out in 20% O2), on blastocyst rate and relative mRNA abundance of some apoptosis‐related genes measured by real‐time qPCR in immature and in vitro‐matured buffalo oocytes and in embryos at 2‐, 4‐, 8‐ to 16‐cell, morula and blastocyst stages. The blastocyst rate was significantly higher (p < 0.05) while the percentage of TUNEL‐positive cells was significantly lower (p < 0.05) under 5% O2 than that under 20% O2. The mRNA expression of anti‐apoptotic genes BCL‐2 and MCL‐1 was significantly higher (p < 0.05) and that of pro‐apoptotic genes BAX and BID was lower (p < 0.05) under 5% O2 than that under 20% O2 concentration at many embryonic stages. Following cysteamine supplementation, the blastocyst rate and the relative mRNA abundance of BCL‐XL and MCL‐1 was significantly higher (p < 0.05) and that of BAX but not BID was lower (p < 0.05) at many stages of embryonic development, although it did not affect the percentage of TUNEL positive cells in the blastocysts significantly. The mRNA expression pattern of these genes during embryonic development was different in 5% vs 20% O2 groups and in cysteamine supplemented vs controls. At the 8‐ to 16‐cell stage, where developmental block occurs in buffalo, the relative mRNA abundance of BCL‐2 and MCL‐1 was highest under 5% O2 concentration and that of BAX and BID was highest (p < 0.05) under 20% O2 concentration. These results suggest that one of the mechanisms through which beneficial effects of low O2 concentration and cysteamine supplementation are mediated during in vitro embryo production is through an increase in the expression of anti‐apoptotic and a decrease in the expression of pro‐apoptotic genes. 相似文献
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This article examines the job expectations of applicants as reported by recruiters interviewing food-supply veterinary medicine (FSVM) candidates and the career-choice decision factors used by year 3 and 4 veterinary students pursuing careers in FSVM. The responses of 1,047 veterinary recruiters and 270 year 3 and 4 students with a food-supply focus from 32 colleges of veterinary medicine in the United States and Canada were examined. Recruiters were asked to report the two most important job factors applicants took into account when deciding to accept an offer; students were asked the two most important reasons for choosing a career in FSVM and the two most important benefits of working as a food-supply veterinarian. Recruiters reported that high salaries and good benefits are the two most important decision factors. Interest in the food-animal career area and a desire for a rural, outdoor lifestyle were the top reasons students gave for choosing an FSVM career. Students saw the enjoyment of working with and helping producers and food animals as the most important benefits of a career in FSVM. 相似文献
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V Vescoli L Degiorgi W Henderson G Gruner KP Starkey LK Montgomery 《Science (New York, N.Y.)》1998,281(5380):1181-1184
Optical experiments were conducted on a series of organic linear chain conductors with different values of the interchain single-electron transfer integral tb, which quantifies the degree of anisotropy. Electron-electron interactions together with Umklapp scattering resulted in a correlation gap and an insulating state for small tb. An insulator-to-metal transition was observed when tb exceeded a critical value, on the order of the correlation gap Egap. The absence of a plasma edge on the insulator side of the transition for polarization perpendicular to the chains suggests that the electrons are confined to the chains. The optical features of the metallic state, when contrasted with the magnetic properties, are suggestive of spin-charge separation. 相似文献