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排序方式: 共有93条查询结果,搜索用时 15 毫秒
1.
Anna Esposito Daniele DAlonzo Stefano DErrico Eliana De Gregorio Annalisa Guaragna 《Marine drugs》2020,18(11)
In the effort to improve the antimicrobial activity of iminosugars, we report the synthesis of lipophilic iminosugars 10a–b and 11a–b based on the one-pot conjugation of both enantiomeric forms of N-butyldeoxynojirimycin (NBDNJ) and N-nonyloxypentyldeoxynojirimycin (NPDNJ) with cholesterol and a succinic acid model linker. The conjugation reaction was tuned using the established PS-TPP/I2/ImH activating system, which provided the desired compounds in high yields (94–96%) by a one-pot procedure. The substantial increase in the lipophilicity of 10a–b and 11a–b is supposed to improve internalization within the bacterial cell, thereby potentially leading to enhanced antimicrobial properties. However, assays are currently hampered by solubility problems; therefore, alternative administration strategies will need to be devised. 相似文献
2.
Gregorio Egea Pedro A. Nortes Rafael Domingo Alain Baille Alejandro Pérez-Pastor María M. González-Real 《Irrigation Science》2013,31(3):445-454
This study assesses the long-term suitability of regulated (RDI) and sustained deficit irrigation (SDI) implemented over the first six growing seasons of an almond [Prunus dulcis (Mill.) D.A. Webb] orchard grown in a semiarid area in SE Spain. Four irrigation treatments were assessed: (i) full irrigation (FI), irrigated to satisfy maximum crop evapotranspiration (100% ETc); (ii) RDI, as FI but receiving 40% ETc during kernel-filling; (iii) mild-to-moderate SDI (SDImm), irrigated at 75–60% ETc over the entire growing season; and (iv) moderate-to-severe SDI (SDIms), irrigated at 60–30% ETc over the whole season. Application of water stress from orchard establishment did not amplify the negative effects of deficit irrigation on almond yield. Irrigation water productivity (IWP) increased proportionally to the mean relative water shortage. SDIms increased IWP by 92.5%, reduced yield by 29% and applied 63% less irrigation water. RDI and SDImm showed similar productive performances, but RDI was more efficient than SDImm to increase fruiting density and production efficiency (PE). We conclude that SDIms appears to be a promising DI option for arid regions with severe water scarcity, whereas for less water-scarce areas RDI and SDImm behaved similarly, except for the ability of RDI to more severely restrict vegetative development while increasing PE. 相似文献
3.
Rotacio S. Gravoso Nestor O. Gregorio Maria Anabelle D. Gerona Moises Neil V. Seri?o Steve R. Harrison Herville V. Pajaron Jayson V. Godoy 《Small-Scale Forestry》2011,10(4):473-488
Through a series of workshops with the stakeholders including nursery operators, tree farmers, staff of the Department of
Environment and Natural Resources, local government units and the academe, a forestry seedling nursery accreditation policy
was developed. The resulting policy was subsequently implemented by the municipal government of Palompon, Leyte. The accreditation
policy encouraged nursery operators to follow smallholder-based best management practices for tree nurseries. Implementation
of the nursery accreditation policy improved farmers’ knowledge and skills in the production of high quality seedlings, encouraged
adoption of BMP for forest nurseries, provided additional source of income for the farmers, enabled members of the groups
operating the communal nursery to forge closer relationship with each other, encouraged utilization of farmers’ free time
in productive activities, developed farmers’ confidence in producing high quality planting materials, and gained for the farmers
favourable attention from various organizations and groups. The Bennett’s hierarchy of project outcomes showed that the implementation
of accreditation scheme achieved high levels of outcomes, indicating that it led to substantial improvements in the lives
of the farmers. 相似文献
4.
Jean‐Marie Séquaris Gregorio Guisado Maria Magarinos Carlos Moreno Peter Burauel Hans‐Dieter Narres Harry Vereecken 《植物养料与土壤学杂志》2010,173(5):699-705
According to recent conceptual models, the organic carbon (OC) of soils can be divided into OC fractions of increasing stability from labile free OC to resistant OC associated with the soil mineral phase. In this study, we present a method for quantifying two OC fractions based on soil aggregate–size fractionation and the N2 gas–adsorption method. For this purpose, we analyzed soil material of the plow layer of a Haplic Chernozem subjected to different fertilizer treatments (no fertilizer, mineral fertilizer, mineral and organic fertilizer). The total organic‐C concentration (TOC) and the clay content of the different size fractions were determined as well as the specific surface area (SSAmineral) and the sample pore volume after thermal oxidation (OC‐free). The TOC of the different soil‐aggregate fractions was linearly related to SSAmineral. Clay‐associated OC and nonassociated OC fractions of the different soil samples were quantified using two methods based on the OC surface loading at the clay fraction. The application of organic fertilizer increased the amount of nonassociated OC but hardly affected the concentration of clay‐associated OC. This finding agrees with previous studies on C dynamics in soils and indicates a finite capacity of soil materials to sequester OC. Even without any addition of organic fertilizer, the mineral phase of the analyzed soil material appears to be C‐saturated. 相似文献
5.
This paper presents results of survey research into the role of the forestry nursery sector in the development of smallholder
forestry in Leyte, Philippines. Seedling production in the province is basically carried out by three categories of nurseries:
individual, communal and the government. Seedlings in the government nurseries are primarily raised for free distribution
to landholders but the extension scheme fails to reach the majority of the smallholder farmers. Seedling demand of landholders
is mostly catered for by the more numerous and accessible individual and communal nurseries. However, problems of capital
outlay, sources and supply of germplasm, technical knowledge in nursery management for both timber and fruit trees and low
sales are among the major impediments in the sustainability of small-scale nurseries. Most of the communal nurseries fail
to sustain the operation after the withdrawal of supporting agencies. Knowledge on site-species matching is needed not only
by small-scale nursery operators but also by the managers of government nurseries. It is concluded that the seedling industry
in the province is not well established and there is a need to organise better the overall nursery system so as to improve
the availability of seedlings and promote appropriate site and species combinations. 相似文献
6.
Romina?P.?SuárezEmail author Maria?E.?Zaccagnini Kimberly?J.?Babbitt Noela?C.?Calamari Guillermo?S.?Natale Alexis?Cerezo Nadia?Codugnello Teresa?Boca Maria?J.?Damonte Josefina?Vera-Candioti Gregorio?I.?Gavier-Pizarro 《Landscape Ecology》2016,31(10):2485-2505
Context
Amphibians are declining worldwide and land use change to agriculture is recognized as a leading cause. Argentina is undergoing an agriculturalization process with rapid changes in landscape structure.Objectives
We evaluated anuran response to landscape composition and configuration in two landscapes of east-central Argentina with different degrees of agriculturalization. We identified sensitive species and evaluated landscape influence on communities and individual species at two spatial scales.Methods
We compared anuran richness, frequency of occurrence, and activity between landscapes using call surveys data from 120 sampling points from 2007 to 2009. We evaluated anuran responses to landscape structure variables estimated within 250 and 500-m radius buffers using canonical correspondence analysis and multimodel inference from a set of candidate models.Results
Anuran richness was lower in the landscape with greater level of agriculturalization with reduced amount of forest cover and stream length. This pattern was driven by the lower occurrence and calling activity of seven out of the sixteen recorded species. Four species responded positively to the amount of forest cover and stream habitat. Three species responded positively to forest cohesion and negatively to rural housing. Two responded negatively to crop area and diversity of cover classes.Conclusions
Anurans within agricultural landscapes of east-central Argentina are responding to landscape structure. Responses varied depending on species and study scale. Life-history traits contribute to responses differences. Our study offers a better understanding of landscape effects on anurans and can be used for land management in other areas experiencing a similar agriculturalization process.7.
Herd CD Blinova A Simkus DN Huang Y Tarozo R Alexander CM Gyngard F Nittler LR Cody GD Fogel ML Kebukawa Y Kilcoyne AL Hilts RW Slater GF Glavin DP Dworkin JP Callahan MP Elsila JE De Gregorio BT Stroud RM 《Science (New York, N.Y.)》2011,332(6035):1304-1307
The complex suite of organic materials in carbonaceous chondrite meteorites probably originally formed in the interstellar medium and/or the solar protoplanetary disk, but was subsequently modified in the meteorites' asteroidal parent bodies. The mechanisms of formation and modification are still very poorly understood. We carried out a systematic study of variations in the mineralogy, petrology, and soluble and insoluble organic matter in distinct fragments of the Tagish Lake meteorite. The variations correlate with indicators of parent body aqueous alteration. At least some molecules of prebiotic importance formed during the alteration. 相似文献
8.
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10.
Velarde R Mentaberre G Sánchez J Marco I Lavín S 《Veterinary journal (London, England : 1997)》2008,177(3):445-447
Gastrointestinal mesenchymal tumours from two Spanish ibex (Capra pyrenaica hispanica) were examined grossly, histologically and immunohistochemically. One neoplasm was a 1.5 kg tan multinodular cavitated mass in the forestomach. The other tumour was a firm mural mass 1.2 cm in diameter in the colon. Microscopically, both tumours were formed mainly by spindle shaped cells arranged in closely packed interlacing fascicles. Neoplastic cells in both tumours labelled positively for KIT (CD117), vimentin and alpha-smooth muscle actin. These findings suggest that both neoplasms were gastrointestinal stromal tumours and most likely to be derived from the interstitial cells of Cajal or their progenitor cells. 相似文献