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排序方式: 共有103条查询结果,搜索用时 0 毫秒
1.
Cavaletto Giacomo Faccoli Massimo Marini Lorenzo Spaethe Johannes Giannone Filippo Moino Simone Rassati Davide 《Journal of pest science》2021,94(3):871-883
Journal of Pest Science - Longhorn beetles are commonly moved among continents within wood packaging materials used in trades. Visual inspections carried out at points of entry often fail to detect... 相似文献
2.
Alfredo Di Filippo Alfredo Alessandrini Franco Biondi Silvia Blasi Luigi Portoghesi Gianluca Piovesan 《Annals of Forest Science》2010,67(7):706-706
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• We combined stem volume increment analysis with dendroecological tools to address two unresolved issues concerning oak dieback
in Mediterranean areas: early detection of changes in stand growth, and identification of mechanisms for observed growth declines. 相似文献
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Filippo Bargnesi Stefano Gridelli Carlo Cerrano Francesco Ferretti 《水产资源保护:海洋与淡水生态系统》2020,30(5):915-927
5.
Tatiana Fioravanti Filippo Bargnesi Andrea Splendiani Massimo Giovannotti Francesca Renzi Vincenzo Caputo Barucchi 《水产资源保护:海洋与淡水生态系统》2020,30(5):892-902
6.
Marilia Barreca Virginia Span Alessandra Montalbano Mercedes Cueto Ana R. Díaz Marrero Irem Deniz Ayegül Erdoan Lada Luki Bilela Corentin Moulin Elisabeth Taffin-de-Givenchy Filippo Spriano Giuseppe Perale Mohamed Mehiri Ana Rotter Olivier P. Thomas Paola Barraja Susana P. Gaudêncio Francesco Bertoni 《Marine drugs》2020,18(12)
The marine environment is a rich source of biologically active molecules for the treatment of human diseases, especially cancer. The adaptation to unique environmental conditions led marine organisms to evolve different pathways than their terrestrial counterparts, thus producing unique chemicals with a broad diversity and complexity. So far, more than 36,000 compounds have been isolated from marine micro- and macro-organisms including but not limited to fungi, bacteria, microalgae, macroalgae, sponges, corals, mollusks and tunicates, with hundreds of new marine natural products (MNPs) being discovered every year. Marine-based pharmaceuticals have started to impact modern pharmacology and different anti-cancer drugs derived from marine compounds have been approved for clinical use, such as: cytarabine, vidarabine, nelarabine (prodrug of ara-G), fludarabine phosphate (pro-drug of ara-A), trabectedin, eribulin mesylate, brentuximab vedotin, polatuzumab vedotin, enfortumab vedotin, belantamab mafodotin, plitidepsin, and lurbinectedin. This review focuses on the bioactive molecules derived from the marine environment with anticancer activity, discussing their families, origin, structural features and therapeutic use. 相似文献
7.
Filippo Scarpa Silvia Sabattini Giuliano Bettini 《Veterinary and comparative oncology》2016,14(3):i-i
The cover image, by Giuliano Bettini et al., is based on the Original Article Cytological grading of canine cutaneous mast cell tumours, DOI: 10.1111/vco.12090 .
8.
Aiuti A Slavin S Aker M Ficara F Deola S Mortellaro A Morecki S Andolfi G Tabucchi A Carlucci F Marinello E Cattaneo F Vai S Servida P Miniero R Roncarolo MG Bordignon C 《Science (New York, N.Y.)》2002,296(5577):2410-2413
Hematopoietic stem cell (HSC) gene therapy for adenosine deaminase (ADA)-deficient severe combined immunodeficiency (SCID) has shown limited clinical efficacy because of the small proportion of engrafted genetically corrected HSCs. We describe an improved protocol for gene transfer into HSCs associated with nonmyeloablative conditioning. This protocol was used in two patients for whom enzyme replacement therapy was not available, which allowed the effect of gene therapy alone to be evaluated. Sustained engraftment of engineered HSCs with differentiation into multiple lineages resulted in increased lymphocyte counts, improved immune functions (including antigen-specific responses), and lower toxic metabolites. Both patients are currently at home and clinically well, with normal growth and development. These results indicate the safety and efficacy of HSC gene therapy combined with nonmyeloablative conditioning for the treatment of SCID. 相似文献
9.
Laviano A Meguid MM Rossi-Fanelli F 《Science (New York, N.Y.)》2002,298(5593):539-41; author reply 539-41
10.
Extractable iron and organic matter in the suspended insoluble material of fog droplets 总被引:1,自引:0,他引:1
Valeriana Mancinelli Stefano Decesari Lorenza Emblico Rosemarie Tozzi Filippo Mangani Sandro Fuzzi Maria Cristina Facchini 《Water, air, and soil pollution》2006,174(1-4):303-320
In this work the formation and composition of aggregates between metals and organic material is studied in real fog samples. In a preliminary experiment it has been found that concentrated cloud samples form a yellow-brown precipitate in the presence of Fe(III). Standards of humic acids and fulvic acids co-precipitate with Fe(III), forming similar aggregates i.e. iron-humates (Fe-HA) and iron-fulvates (Fe-FA). By comparing the solubility properties of aggregates by extracting organic carbon (OC) in different pH conditions, it has been observed that fog droplet particulate samples are characterised by solubility properties more similar to those of Fe-HA than Fe-FA. Dilute alkaline solutions can also easily extract organic refractory substances that form aggregates with metals. The recoveries of the total extractable organic matter (accounting for 12% of total insoluble carbon and 15% of particulate mass) are similar to those of humic-like substances (HULIS) from particulate samples. The chromatographic behaviour and functional group characteristics measured in the alkali-extract fraction of precipitated aggregates with iron and in the insoluble particulate of fog samples, are those of humic-like material. Thus, soluble HULIS are able to interact with iron to form particulate, but the composition of a large fraction of insoluble organic carbon is still unknown. These findings have implications on the solubility and surface tension properties of fog droplets and can therefore potentially influence droplet formation, as well as cloud chemical and photochemical processes. 相似文献
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