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Intraosseous Cannulation and Drug Administration for Induction of Anesthesia in Chickens 总被引:2,自引:0,他引:2
ALEXANDER VALVERDE dvm DVSc Diplomate ACVA DOROTHEE BIENZLE DVM MSc DALE A SMITH dvm DVSc DORIS H. DYSON dvm DVSc Diplomate ACVA ANNE E. VALLIANT bsc 《Veterinary surgery : VS》1993,22(3):240-244
Twenty-four chickens were randomly assigned to one of three treatments (ketamine, 30 mg/ kg; thiopental, 20 mg/kg; saline, 0.8 mL). Baseline data (heart rate, respiratory rate, systolic blood pressure, and cloacal temperature) were recorded before ulnar intraosseous cannulation and administration of drug treatment and for 30 minutes after administration. One investigator, unaware of the treatment administered, assessed the reaction to cannulation, number of attempts per cannulation, reaction to injection, time to induction and recovery, and quality of induction and recovery. Respiratory rate increased significantly (p < .05) from baseline after thiopental. Other parameters did not vary within groups or between groups. Most birds did not react or had a mild reaction to cannulation and injection, and on average fewer than two attempts were necessary. Quality of recovery was significantly (p < .05) better after thiopental. Time to recovery was significantly (p < .05) shorter after thiopental. No major histopathologic changes were noted in bone marrow samples from the injection site. This study demonstrates that the intraosseous route may be used to induce anesthesia in chickens, and that minimal changes in the variables studied were produced by ketamine and thiopental. 相似文献
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PETER BÖTTCHER Dr med vet Diplomate ECVS DOROTHEE KRASTEL DVM JOHANNES HIERHOLZER Dr med KERSTIN WESTPHALEN Dr med STEPHANIE FLORIAN Dr med vet GUIDO HILDEBRANDT Dr med GREVEL VERA Dr med vet Diplomate ECVS GERHARD OECHTERING Dr med vet Diplomate ECVAA 《Veterinary surgery : VS》2009,38(7):888-901
Objective— To (1) evaluate the analgesic effect of percutaneous cementoplasty (PC) in dogs with primary bone tumor (PBT) of the distal aspect of the radius and (2) evaluate the impact on the course of disease by adding PC to a palliative, multimodal treatment protocol in these dogs.
Study Design— Prospective pilot study.
Animals— Dogs (n=4) with PBT of the distal aspect of the radius.
Methods— Tumor lesions were filled percutaneously with polymethylmethacrylate under fluoroscopic guidance. Pamidronate was administered once in a week before PC. Radiotherapy and chemotherapy were initiated 2 and 6 weeks after PC, respectively. Force plate analysis was performed immediately before 2, and 6 weeks after PC. Survival time was defined from PC to euthanasia.
Results— Two dogs had a significant increase in peak vertical force 2 weeks after PC ( P =.043) and remained free of lameness for 18 and 20 weeks, respectively. One dog had an acute relapse after an initially lame-free period of 10 days. The remaining dog failed to improve ( P =.686). Three dogs developed at least 2 complications including transient worsening of the lameness after PC, cement leakage, wound infection and suspected thromboembolism in combination with cough and anemia. Median survival was 4.8 months (range, 1–5.7 months).
Conclusions— PC in combination with pamidronate significantly improved lameness in 2 dogs; however, PC is not risk-free. Deep wound infection, intraarticular cement leakage, and venous thrombosis were the main complications.
Clinical Relevance— PC might be a useful addition to established palliative, multimodal treatment protocols in dogs with PBT; however, because of the complications encountered PC warrants further study before routine use can be considered. 相似文献
Study Design— Prospective pilot study.
Animals— Dogs (n=4) with PBT of the distal aspect of the radius.
Methods— Tumor lesions were filled percutaneously with polymethylmethacrylate under fluoroscopic guidance. Pamidronate was administered once in a week before PC. Radiotherapy and chemotherapy were initiated 2 and 6 weeks after PC, respectively. Force plate analysis was performed immediately before 2, and 6 weeks after PC. Survival time was defined from PC to euthanasia.
Results— Two dogs had a significant increase in peak vertical force 2 weeks after PC ( P =.043) and remained free of lameness for 18 and 20 weeks, respectively. One dog had an acute relapse after an initially lame-free period of 10 days. The remaining dog failed to improve ( P =.686). Three dogs developed at least 2 complications including transient worsening of the lameness after PC, cement leakage, wound infection and suspected thromboembolism in combination with cough and anemia. Median survival was 4.8 months (range, 1–5.7 months).
Conclusions— PC in combination with pamidronate significantly improved lameness in 2 dogs; however, PC is not risk-free. Deep wound infection, intraarticular cement leakage, and venous thrombosis were the main complications.
Clinical Relevance— PC might be a useful addition to established palliative, multimodal treatment protocols in dogs with PBT; however, because of the complications encountered PC warrants further study before routine use can be considered. 相似文献
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