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Chin-Soon Phan Shean-Yeaw Ng Eun-A Kim You-Jin Jeon Kishneth Palaniveloo Charles Santhanaraju Vairappan 《Marine drugs》2015,13(5):3103-3115
Two new bicyclogermacrenes, capgermacrenes A (1) and B (2), were isolated with two known compounds, palustrol (3) and litseagermacrane (4), from a population of Bornean soft coral Capnella sp. The structures of these metabolites were elucidated based on spectroscopic data. Compound 1 was found to inhibit the accumulation of the LPS-induced pro-inflammatory IL-1β and NO production by down-regulating the expression of iNOS protein in RAW 264.7 macrophages. 相似文献
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