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The refercnce to Bouguer anomalies in the caption to Fig. 2 of the report by W. H. Kanes et al. (Science, 1 June 1973, p. 950) is in error. Isostatic anomalies are meant.-Ed. 相似文献
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Tight junctions (TJs) in inter-Sertoli junctional areas and epididymal epithelia build up the blood–testis barrier (BTB) and the blood–epididymal barrier (BEB), respectively. In this study, the expression of occludin, an integral member of the TJs, was examined in testis and different regions of epididymis of Lepus sinensis coreanus , an Korean wild rabbit species. In testis, intense occludin immunoreactivity was found in the basally located inter-Sertoli junctional area together with diffused immunoreactivity of occludin in the cytoplasm of Sertoli cells. It can be suggested that occludin is one of the robust elements of BTB in seminiferous tubules of rabbit testis. In proximal and distal caput epididymis, occludin immunoreactivity was found in the lateral as well as apical contacts of epithelial cells. In corpus epididymis, intense occludin immunoreactivity was found in the basolateral as well as apical contacts of epithelial cells together with cytoplasmic signal. In cauda epididymis, occludin immunoreactivity in luminal epithelia was relatively strong but largely found in the cytoplasm. This suggests that intriguing regulatory mechanisms differentially recruit occludin to the TJ in the different regions of epididymal epithelia. The differences in the subcellular localization as well as expression levels of occludin among the epididymal segments may reflect differential paracellular permeability of epithelia along the epididymal tubules and be correlated with sperm maturation in rabbit. In Western blot, a major form of occludin was MW 62 kDa together with small fragments of MW 34–39 kDa in testis and epididymis, suggesting the peptide cleavage of occludin. This is the first report on the molecular nature of TJs in a wild rabbit testis and epididymis. 相似文献
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The formation and development of a zone of spreading beneath the continental crust resulted in the breakup of Pangea and formation of the Atlantic Ocean. The crust of Morocco bears an extremely complete record of the crustal response to this episode of mantle dynamics. Structural and related depositional patterns indicate that the African margin had stabilized by the Middle Jurassic as a marine carbonate environment; that it was dominated by tensile stresses in the early Mesozoic, resulting in two fault systems paralleling the Atlantic and Mediterranean margins and a basin and range structural-depositional style; and that it was affected by late Paleozoic metamorphism and intrusion. Mesozoic events record the latter portion of African involvement in the spreading episode; late Paleozoic thermal orogenesis might reflect the earlier events in the initiation of the spreading center and its development beneath significant continental crust. In that case, more than 100 million years were required for mantle dynamics to break up Pangea. 相似文献
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