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A general allometric model has been derived to predict intraspecific and interspecific scaling relationships among seed plant leaf, stem, and root biomass. Analysis of a large compendium of standing organ biomass sampled across a broad sampling of taxa inhabiting diverse ecological habitats supports the relations predicted by the model and defines the boundary conditions for above- and below-ground biomass partitioning. These canonical biomass relations are insensitive to phyletic affiliation (conifers versus angiosperms) and variation in averaged local environmental conditions. The model thus identifies and defines the limits that have guided the diversification of seed plant biomass allocation strategies. 相似文献
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Atlas R Campbell P Cozzarelli NR Curfman G Enquist L Fink G Flanagin A Fletcher J George E Hammes G Heyman D Inglesby T Kaplan S Kennedy D Krug J Levinson R Marcus E Metzger H Morse SS O'Brien A Onderdonk A Poste G Renault B Rich R Rosengard A Salzburg S Scanlan M Shenk T Tabor H Varmus H Wimmer E Yamamoto K;Journal Editors Authors Group 《Science (New York, N.Y.)》2003,299(5610):1149
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An iron-sulfur compound (Fe3S2) was synthesized at pressures greater than 14 gigapascals in the system Fe-FeS. The formation of Fe3S2 changed the melting relations from a simple binary eutectic system to a binary system with an intermediate compound that melted incongruently. The eutectic temperature in the system at 14 gigapascals was about 400°C lower than that extrapolated from Usselman's data, implying that previous thermal models of Fe-rich planetary cores could overestimate core temperature. If it is found in a meteorite, the Fe3S2 phase could also be used to infer the minimum size of a parent body. 相似文献
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Whistler JL Enquist J Marley A Fong J Gladher F Tsuruda P Murray SR Von Zastrow M 《Science (New York, N.Y.)》2002,297(5581):615-620
Recycling of the mu opioid receptor to the plasma membrane after endocytosis promotes rapid resensitization of signal transduction, whereas targeting of the delta opioid receptor (DOR) to lysosomes causes proteolytic down-regulation. We identified a protein that binds preferentially to the cytoplasmic tail of the DOR as a candidate heterotrimeric GTP-binding protein (G protein)-coupled receptor-associated sorting protein (GASP). Disruption of the DOR-GASP interaction through receptor mutation or overexpression of a dominant negative fragment of GASP inhibited receptor trafficking to lysosomes and promoted recycling. The GASP family of proteins may modulate lysosomal sorting and functional down-regulation of a variety of G protein-coupled receptors. 相似文献
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Pseudorabies virus (PRV), an alpha-herpesvirus, is capable of spreading between synaptically connected neurons in diverse hosts. In this report, two lines of experimentation are summarized that provide insight into the mechanism of virus spread in neurons. First, techniques were developed to measure the transport dynamics of capsids in infected neurons. Individual viral capsids labeled with green fluorescent protein (GFP) were visualized and tracked as they moved in axons away from infected neuronal cell bodies in culture during egress. Second, the effects of three viral membrane proteins (gE, gI and Us9) on the localization of envelope, tegument, and capsid proteins in infected, cultured sympathetic neurons were determined. These three proteins are necessary for spread of infection from pre-synaptic neurons to post-synaptic neurons in vivo (anterograde spread). Us9 mutants apparently are defective in anterograde spread in neural circuits because essential viral membrane proteins such as gB are not transported to axon terminals to facilitate spread to the connected neuron. By contrast, gE and gI mutants manifest their phenotype because these proteins most likely function at the axon terminal of the infected neuron to promote spread. These two sets of experiments are consistent with a model for herpesvirus spread in neurons first suggested by Cunningham and colleagues where capsids and envelope proteins, but not whole virions, are transported separately into the axon. 相似文献
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Two-dimensional strain fields around knots in two Norway spruce specimens subjected to tension loading were detected using a contact-free measuring technique based on white-light digital image correlation. The first specimen included a traversing Edge knot, and the second one, a Centric knot. The development of strain fields as a function of load level was measured by consecutive cyclic load tests where one side of the specimen was studied during each test. The objectives were to examine to what extent the strain fields could be detected, to investigate the correlation between strain fields measured on different sides of a specimen and to analyse the strain distributions around the knots. The results show that the applied technique is useful for catching both overall and detailed information about the behaviour of knots in wood members exposed to loading. Clear wood defects that could not have been detected by neither visual inspection nor scanning were observed, and conclusions could be drawn regarding the release of internal stresses. The correlations between strain fields on different sides of the specimens were excellent, and the correspondence between measurement results and comparative finite element calculations was surprisingly good considering the fact that the employed FE models were fairly simple. 相似文献
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DeFalco J Tomishima M Liu H Zhao C Cai X Marth JD Enquist L Friedman JM 《Science (New York, N.Y.)》2001,291(5513):2608-2613
We report the development of a pseudorabies virus that can be used for retrograde tracing from selected neurons. This virus encodes a green fluorescent protein marker and replicates only in neurons that express the Cre recombinase and in neurons in synaptic contact with the originally infected cells. The virus was injected into the arcuate nucleus of mice that express Cre only in those neurons that express neuropeptide Y or the leptin receptor. Sectioning of the brains revealed that these neurons receive inputs from neurons in other regions of the hypothalamus, as well as the amygdala, cortex, and other brain regions. These data suggest that higher cortical centers modulate leptin signaling in the hypothalamus. This method of neural tracing may prove useful in studies of other complex neural circuits. 相似文献
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Recent syntheses of high-pressure alkali and alkaline earth silicates reveal a class of framework structures with corner-linked 4- and 6-coordinated silicon. These compounds possess the structural formula (A4-2x1+Bx2+)SimVI(SinIVO2(m+n)+2), where x, m, and n specify the amounts of alkaline earth, 6-coordinated silicon, and 4-coordinated silicon, respectively. Appropriate values of m and n yield a range of high-pressure structures, from fully 4-coordinated to fully 6-coordinated silicate frameworks. Recognition of this class of framework silicates leads to predictions of high-pressure structures as well as room-pressure isomorphs of high-pressure silicates. 相似文献
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Savage VM White EP Moses ME Ernest SK Enquist BJ Charnov EL 《Science (New York, N.Y.)》2006,312(5771):198; author reply 198
Nee et al. (Reports, 19 August 2005, p. 1236) used a null model to argue that life history invariants are illusions. We show that their results are largely inconsequential for life history theory because the authors confound two definitions of invariance, and rigorous analysis of their null model demonstrates that it does not match observed data. 相似文献