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Three-year-old, non-lactating and non-pregnant Merino ewes, raised on pasture under a program of strategic treatment with anthelmintic and found to be extremely resistant to "trickle" infection with Haemonchus contortus, were given single-dose infections with either H. contortus or Trichostrongylus colubriformis or both species together. The purpose was to ascertain the intensity of protective immunity against the 2 parasites in sheep with immunity acquired from a presumably slight exposure to infection. To provide a criterion, some infected ewes were immunosuppressed with corticosteroid, dexamethasone. Untreated ewes were extremely resistant to challenge infection with either 15,000 or 150,000 H. contortus or 15,000 T. colubriformis. Surprisingly, when mixed infection was given, egg counts for H. contortus were significantly elevated compared with infection by that species alone. Antibody to antigens from infective larval and adult H. contortus was measured in serum by enzyme-linked-immunosorbent assay (ELISA) during the course of infection. Serum titres against larval antigens were significantly depressed when infections with either H. contortus or T. colubriformis were permitted by immunosuppression with dexamethasone, whereas those against adult antigen were depressed when infection with T. colubriformis was permitted.  相似文献   
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Plague, caused by Yersinia pestis, is a flea-borne disease that is endemic in areas throughout the world due to its successful maintenance in a sylvatic cycle, mainly in areas with temperate climates. Burrowing rodents are thought to play a key role in the enzootic maintenance as well as epizootic outbreaks of plague. In the United States, prairie dogs (Cynomys), rodents (Muridae), and ground squirrels (Spermophilus) are susceptible to infection and are parasitized by fleas that transmit plague. In particular, prairie dogs can experience outbreaks that rapidly spread, which can lead to extirpation of colonies. A number of ecological parameters, including climate, are associated with these epizootics. In this study, we asked whether soil parameters, primarily moisture and temperature, are associated with outbreaks of plague in black-tailed prairie dogs and Gunnison's prairie dogs in the Western United States, and at what depth these associations were apparent. We collected publicly available county-level information on the occurrence of population declines or colony extirpation, while historical soil data was collected from SCAN and USCRN stations in counties and states where prairie dogs have been located. The analysis suggests that soil moisture at lower depths correlates with colony die-offs, in addition to temperature near the surface, with key differences within the landscape ecology that impact the occurrence of plague. Overall, the model suggests that the burrow environment may play a significant role in the epizootic spread of disease amongst black-tailed and Gunnison's prairie dogs.  相似文献   
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Interference of Sinapis arvensis L. (wild mustard) and Chenopodium album L. (lamb's-quarters) in spring rapeseed (Brassica napus L.) was studied under field conditions in 1983 and 1984. Both weed species interfered with rapeseed early in the growing season, causing significant reductions in rapeseed dry weight by June of each year. Sinapis arvensis caused greater rapeseed grain yield reductions than did C. album. With weed densities of 20–80 plants m?2, rapeseed grain yield reductions ranged from 19 to 77% with S. arvensis but only 20 to 25% with C. album. Rapeseed yield reductions caused by mixtures of both weed species ranged from being less than to being equal to the sum of reductions caused by each weed alone, depending on the weed density and year of study. Both weed species were prolific seed producers capable of returning large quantities of seed to the soil. With weed densities ranging from 10–80 plants m?2, S. arvensis produced 5700–30 100 seeds m?2 while C. album produced 3100–63 600 seeds m?2.  相似文献   
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Summary. The root and shoot growth of oat (Avena saliva L.) and squash (Cucurbita maxima Duchesne) was reduced in proportion to propachlor concentration. Corn (Zea mays L.) root growth was inhibited only by concentrations of 16 ppm and higher. Cell division in onion (Allium cepa L.) root tips was reduced by propachlor and totally inhibited by 16 ppm. Auxin-induced cell elongation of oat coleoptiles was inhibited in proportion to propachlor concentration. Propachlor treatment prevented the normal senescence of squash cotyledons by inhibiting the autolysis of proteinaceous and lipid reserves. Effets morphologiques, anatomiques et biochimiques du propachlore sur la croissance des plantules Riisumi.  相似文献   
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A single dose of 5 x 10(8) bacilli of Pseudomonas pseudomallei by intratracheal injection resulted in acute (21 cases) or chronic (19 cases) melioidosis in 40 of 48 pigs. Fifteen (10 acute and 5 chronic) had been immunosuppressed by cyclophosphamide before inoculation. The major clinical signs were initial fever, marked neutrophilia and, in the acute cases, respiratory distress. There were no signs of the nasal and ocular discharge, paresis or diarrhoea seen in acute cases in south-east Asia. The cyclophosphamide treatment caused a significant decrease in the neutrophil count by 7 d after inoculation in all 15 immunosuppressed pigs, and all were culture positive at necropsy. Eight of the 33 non-treated pigs were culture negative at necropsy. Pigs overcoming the initial phase of infection had more abscess-like nodules that were bacteriologically sterile at necropsy than the pigs with acute cases of melioidosis. P. pseudomallei was isolated predominantly from the spleen, lungs and the injection site. Although only one strain was used in this study, it is likely that Australian strains of P. pseudomallei are not as virulent as the south-east Asian isolates.  相似文献   
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