高锰酸钾共振瑞利散射法测定磺胺二甲嘧啶

在0.2 mol/L H_2SO_4介质中,磺胺二甲嘧啶(SM_2)和KMnO_4在加热条件下发生氧化还原反应生成MnO_2微粒,导致共振瑞利散射(RRS)增强,并产生新的散射峰.其最大散射波长位于595 nm附近,散射强度在一定范围内与SM_2的浓度成正比,据此建立了测定SM_2的共振瑞利散射(RRS)新方法.本方法具有较高的灵敏度,检出限为8.6 ng/mL.实验优化了测定条件.考察了共存物质的影响,表明方法具有良好的选择性,用于片剂中SM_2的测定,结果满意.

Abstract：

In 0.20 mol/L H_2SO_4 medium, a redox reaction took place between sulfadimidine (SM_2) and po-tassium permanganate to form MnO_2 particles by heating.As a result, new spectra of resonance rayleigh scattering appeared and their intensities were enhanced greatly.The maximum peak of RRS was located at approximately 595 nm, and the scattering intensities were proportional to the concentration of SM_2.Based on these results, a new method for the determination of SM_2 was established.The detection limit (3σ) was 8.6 ng/mL.The effects of coexistent substances were tested, and the results demonstrated that this meth-od had good selectivity.It has been applied to the determination of SM_2 in tablets with satisfactory results.     

钯(Ⅱ)-托拉塞米反应体系的共振瑞利散射和共振非线性散射光谱及其分析应用

在pH=4.0～7.0的Britton-Robinson(BR)缓冲溶液中,托拉塞米与Pd(Ⅱ)形成1:1的螯合物,此时将引起共振瑞利散射(RRS)、二级散射(SOS)和倍频散射(FDS)显著增强,其最大RRS,SOS和FDS波长分别位于340,586,349 nm附近,在一定范围内,3种散射增强与托拉塞米的浓度成正比,方法具有较高的灵敏度,对托拉塞米的检出限(3σ)在1.1～5.5 ng/mL之间.考察了适宜的反应条件及共存物质的影响,表明方法有良好的选择性.据此,提出了测定痕量托拉塞米的灵敏、简便和快速的新方法.