The effect of erector spinae plane block on perioperative analgesic consumption and complications in dogs undergoing hemilaminectomy surgery: a retrospective cohort study

ObjectiveTo compare the perioperative use of analgesics and complication rates in dogs administered an erector spinae plane (ESP) block or a traditional opioid-based (OP) treatment as part of analgesic management during hemilaminectomy.Study designRetrospective cohort study.AnimalsMedical records of 114 client-owned dogs.MethodsGeneral data included demographics, duration of procedure, number of laminae fenestrated, perioperative use of steroid and non-steroidal anti-inflammatory drugs. Intra- and postoperative analgesics used in 48 hours and complications rates were compared between groups. Opioid use was expressed in morphine equivalents [ME (mg kg^?1)]. Continuous data were compared using the Mann–Whitney U test and incidence of events with a Fisher's exact tests. Multiple linear regression was used to evaluate association between perioperative ME consumption (dependent variable) with other independent variables. Data are presented as median (range). Differences were considered significant when p < 0.05.ResultsGroup ESP comprised 42 dogs and group OP 72 dogs. No differences were observed in the general data. Intraoperative ME was 0.65 (0.20–3.74) and 0.79 (0.19–5.60) mg kg^?1 in groups ESP and OP, respectively (p = 0.03). Intraoperative infusion of lidocaine was administered intravenously (IV) to 23.8% and 68% of groups ESP and OP, respectively (p < 0.0001). Intraoperative infusion of ketamine was administered IV to 21% and 40% of groups ESP and OP, respectively (p = 0.04). Regression analysis revealed the ESP block as the only independent variable affecting the perioperative ME consumption. Pharmacological intervention to treat cardiovascular complications was administered to 21.4% and 47.2% of dogs in groups ESP and OP, respectively (p = 0.008). There were no differences in postoperative complication rates.Conclusions and clinical relevanceESP block was associated with reduced perioperative opioid consumption, intraoperative adjuvant analgesic use and incidence of pharmacological interventions to treat cardiovascular complications in dogs undergoing hemilaminectomy.     

湖南省麦迪卡药石农业应用效果综述

湖南省麦迪卡药石(MEDCAL STONE)资源丰富,质量优良,具有富硅、富钾、富微量元素和离子轻稀土的特点,具有很强的吸附性能,可溶出多种有益矿物质,增加水中氧的含量,调节水的pH值,生物活性强,对防治疾病具有重要作用。经过近20 a的研究,农业上应用在作物施肥、药膳食疗等方面,均有极好的社会、经济效益。同时,产地水土、森林、人文资源特好,生态景观优美,不但是天然的无公害农业基地,也是发展休闲农业、旅游农业的"风水宝地"。     

Histopathological effects of cadmium on the gills of the freshwater fish, Macropsobrycon uruguayanae Eigenmann (Pisces, Atherinidae)

Evaluations of histopathological lesions in gill tissue were carried out in the freshwater fish Macropsobrycon uruguayanae following 30 and 60 days of exposure to 1.5 mg 1^-1 of cadmium. The study was conducted on both fed and starved animals in order to determine the influence of feeding condition on cadmium toxicity. The main lesions observed and quantified were: (1) hyperplasia of primary lamellar epithelium; (2) hyperplasia of secondary lamellar epithelium; (3) separation of respiratory epithelium; (4) shortening of secondary lamellae; (5) epithelial necrosis; (6) fusion of adjacent secondary lamellae; (7) hypertrophy of respiratory epithelium; (8) lamellar telangiectasis; (9) hyperplasia of chloride cells; (10) mucinous metaplasia; and (11) inflammatory infiltration. Lesions 6, 8, 9 and 11 were only induced by exposure to cadmium, while lesion 4 could be produced only by starvation. Starved fish also showed a reduction in total body weight and length. Lesion 2 was shown to be non-specific, and produced by either cadmium, starvation or even exposure time. The possible mode of action of the experimental factors are discussed in relation to the observed pathologies.     

Acute tolerance and histopathological effects of ammonia on juvenile maroon clownfish Premnas biaculeatus (Block 1790)

This study evaluated the median lethal concentration values (LC₅₀) and the histopathological effects of un‐ionized ammonia (NH₃^‐‐N) on juvenile maroon clownfish Premnas biaculeatus. After 96 h of exposure to different concentrations of ammonia, juveniles were sampled for histopathological evaluation. The 24 and 96 h LC50 values of NH₃^?‐N determined were 1.68 and 0.89 mg L^?1 respectively. Maroon clownfish exposed to different ammonia concentrations displayed histopathological alterations in the gills, kidney, liver and brain. Gill tissue damage included lamellar hyperplasia, lamellar shorting and hyperplasia and hypertrophy of mucous cells. The kidney showed hyperanaemia, enlarged sinusoids within an apparently decreased amount of haematopoietic tissue, oedema on tubular cells and tubular necrosis, and an enlarged Bowman's capsule. The liver presented dilatation of hepatic sinusoids, fatty deposition in hepatocytes and Mallory bodies. Examination of the brain revealed a proliferation of glial cells, and the Virchow‐Robin space indicated a severe perivascular oedema and signs of neuronal suffering with satellitosis. The results of this study indicate that juvenile maroon clownfish are relatively sensitive to ammonia and particular attention must be given to this toxic compound in culture systems.     

Ontogenetic movements of juvenile blacktip reef sharks: evidence of dispersal and connectivity between coastal habitats and coral reefs

相似文献   

日光温室内反光膜补光的实践与理论探析

试验结果表明 ,温室后墙悬挂反光膜进行补光后 ,对温室内测定点处最大光照度值无影响 ,但平均提高测定点处水平光照度值 15 4 8% ;温室内凌晨时气温、地温、墙温和被反光膜遮掩处墙温分别比对照温室低 1 1℃、1 5℃、0 9℃和 1 8℃ ,但正午时分别比对照温室高 1 6℃、1 4℃、0 3℃和低 11 4℃。温室经济产量增加 7 4 % ,当期经济效益增加 2 1元 /m2 。     

不同栽培模式及施氮量对半旱地冬小麦氮素累积及分配的影响

【目的】研究不同栽培模式和施氮量对半旱地栽培条件下冬小麦-夏玉米轮作体系中冬小麦地上部氮素累积、分配及利用效率的影响。【方法】在陕西关中地区进行了田间试验,以常规栽培为对照,比较了补灌、覆草和垄沟等栽培模式及0,120,240 kg/hm2施氮水平,对冬小麦连续2年(2004和2005年)不同生长期各部位氮素累积量的影响。【结果】在补灌模式下,2004和2005年成熟期冬小麦叶片和茎秆的氮素累积量较其他模式低,氮素分配率也较低,而籽粒的氮素分配率较高;施用氮肥显著增加了各生长时期冬小麦叶片、茎秆、颖壳和穗轴以及籽粒的氮素累积量,当氮肥施用量由120增加到240 kg/hm2时,除籽粒外,成熟期冬小麦叶片、茎秆、颖壳和穗轴的氮素残留量均随之明显增加。与不同栽培模式相比,施用氮肥对冬小麦不同器官中氮素分配的影响较小。随着氮肥施用量的增加,氮肥利用效率、氮肥农学效率和氮肥生理效率均呈降低趋势。在不同栽培模式中,连续2年补灌栽培模式下冬小麦的氮肥利用效率、氮肥农学效率以及氮肥生理效率均较高,而其他栽培模式下这3个指标年际间的变化较大。【结论】施用氮肥可显著增加冬小麦各生长时期不同器官的氮素累积量,但对氮素在不同器官中分配比例的影响较小;与施用氮肥相比,不同栽培模式对冬小麦氮素的累积、分布无明显影响;冬季补灌有利于提高冬小麦的氮素效率。