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1.
Canfield PJ Watson AD Ratcliffe RC 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》1987,16(1):21-28
Dyserythropoiesis characterized by enhanced intramedullary destruction, pathologic sideroblasts and siderocytes, and hemoglobin crystallization was detected in a female Cocker Spaniel presented for poor exercise tolerance. Examination of peripheral blood revealed intraerythrocytic crystals, granulation of erythrocytes, nucleated erythroid cells, reticulocytosis and marked variation in erythrocyte morphology in the absence of anemia. Bone marrow examination revealed sideroblasts, a low M:E ratio and evidence of enhanced intramedullary destruction of erythroid cells. Electron microscopy of peripheral blood and bone marrow confirmed pathologic mitochondrial iron accumulation in erythroid cells and the presence of intraerythrocytic hemoglobin crystals. A cause for the hematologic changes was not identified. After the animal became clinically normal, siderocytes disappeared from peripheral blood but intraerythrocytic crystals and reticulocytosis persisted. 相似文献
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Key Factors Affecting Reproductive Success of Thoroughbred Mares and Stallions on a Commercial Stud Farm
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EA Lane MLJ Bijnen M Osborne SJ More ISF Henderson P Duffy MA Crowe 《Reproduction in domestic animals》2016,51(2):181-187
To evaluate factors contributing to fertility of thoroughbred mares, data from 3743 oestrous periods of 2385 mares were collected on a large thoroughbred farm in Ireland. Fourteen stallions (mean age 8.3 years; range 4–15 years) had bred 2385 mares (mean age 9.4 years; range 3–24 years). Maiden mares accounted for 12%, mares with a foal at foot for 64%, and barren, slipped or rested mares for 24% of the total. The mean pregnancy rate per cycle was 67.8% (68.6% in year 1 and 66.9% in year 2). Backward stepwise multivariable logistic regression analysis was utilized to develop two models to evaluate mare factors, including mare age, reproductive status, month of foaling, dystocia, month of cover, foal heat, cycle number, treatments, walk‐in status and stallion factors including stallion identity, stallion age, shuttle status, time elapsed between covers and high stallion usage on the per cycle pregnancy rate and pregnancy loss. Old age (p < 0.001) and cover within 20 days post‐partum (p < 0.003) were associated with lowered pregnancy rates. High mare age (p < 0.05) and barren, slipped or rested reproductive status (p = 0.05) increased the likelihood of pregnancy loss. Uterine inflammation or infection, if appropriately treated, did not affect fertility. Only high usage of stallions (used more than 21 times in previous week) was associated with lowered (p = 0.009) pregnancy rates. However, shuttle stallions were more likely to have increased (p = 0.035) pregnancy survival, perhaps reflecting a bias in stallion selection. In conclusion, mare age exerted the greatest influence on fertility; nonetheless, thoroughbreds can be effectively managed to achieve high reproductive performance in a commercial setting. 相似文献
3.
The effects of vaccination of Merino ewes with an attenuated Australian bluetongue virus serotype 23 at different stages of gestation 总被引:1,自引:0,他引:1
SUMMARY A cell culture attenuated Australian bluetongue virus serotype 23 (BLU23) prototype vaccine was assessed for its effects on pregnant Merino sheep. Seventy-six ewes were vaccinated at 5 different stages of gestation, and the failure to lamb at term was as follows: 35 to 43 days of gestation, 20/36 (56%); 57 to 64 days of gestation, 3/10 (30%); 81 to 88 days of gestation, 3/10 (30%); 109 to 116 days of gestation, 0/10 (0%); 130 to 137 days of gestation, 0/10 (0%). Of 30 ewes vaccinated with a cell culture supernatant fluid control between 35 and 43 days of gestation, 6.7% (2/30) failed to lamb at term. Two ewes vaccinated with BLU23 vaccine between 35 and 43 days of gestation had lambs with hydranencephaly. All other lambs born were clinically normal. Three ewes vaccinated with BLU23 aborted. Two of these were vaccinated between 35 and 43 days of gestation, the 3rd between 81 and 88 days of gestation. Five lambs were born with BLU group antibody. Four of these were from ewes vaccinated between 35 and 43 days of gestation, and 2 of these had hydranencephaly. The fifth was from a ewe vaccinated between 57 and 64 days of gestation. The vaccine did not produce disease in adult sheep, but was a potent cause of early foetal death and to a much lesser extent foetal malformation. 相似文献
4.
Ratcliffe MJ 《Veterinary immunology and immunopathology》2002,87(3-4):337-340
B lymphocyte development can occur in a variety of anatomical sites. While typically considered to be a process that occurs in the bone marrow throughout life, it is becoming clear that gut associates sites of B cell development are critically important in many species of veterinary importance. Among these sites, the bursa of Fabricius in chickens and the ileal Peyer's patches of sheep are among the best studied. In these organs, it has become clear that many of the properties associated with B cell development in rodent and primate bone marrow do not apply. Thus while bone marrow B cell development typically involves an ongoing maturation of mature B cells from immature B lineage precursors that lack the expression of a surface immunoglobulin complex, gut associated lymphoid tissues (GALTs) may be colonized by a single wave of precursor cells during embryo development. Nonetheless, molecular analysis of the requirements for B lymphocyte development in GALTs reveals some striking parallels with requirements identified for B cell development in bone marrow. This article will discuss differences between B cell development in the bone marrow and GALTs and recent evidence emerging that yields insights into how these processes are regulated. 相似文献
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Blaise Ratcliffe Foster J. Hart Jaroslav Klápště Barry Jaquish Shawn D. Mansfield Yousry A. El-Kassaby 《Annals of Forest Science》2014,71(3):415-424
Context
Wood quality traits are important to balance the negative decline of wood quality associated with selection for growth attributes in gymnosperm breeding programs. Obtaining wood quality estimates quickly is crucial for successful incorporation in breeding programs.Aims
The aims of this paper are to: (1) Estimate genetic and phenotypic correlations between growth and wood quality attributes, (2) Estimate heritability of the studied traits, and (3) Assess the accuracy of in situ non-destructive tools as a representative of actual wood density.Methods
Wood density (X-ray densitometry), tree height, diameter, volume, resistance drilling, acoustic velocity, and dynamic modulus of elasticity were estimated, along with their genetic parameters, for 1,200, 20-year-old trees from 25 open-pollinated families.Results
Individual tree level heritabilities for non-destructive evaluation attributes were moderate ( $ {\widehat{h}}_i^2=0.37-0.42 $ ), wood density and growth traits were lower ( $ {\widehat{h}}_i^2=0.23-0.35 $ ). Favorable genetic and phenotypic correlations between growth traits, wood density, and non-destructive evaluation traits were observed. A perfect genetic correlation was found between resistance drilling and wood density (r G ?=?1.00?±?0.07), while acoustic velocity and dynamic modulus of elasticity showed weaker genetic correlations with wood density (r G ?=?0.25?±?0.24;?0.46?±?0.21, respectively).Conclusion
This study confirmed that resistance drilling is a reliable predictor of wood density in western larch, while the weak genetic correlations displayed by acoustic velocity and dynamic modulus of elasticity suggest limited dependability for their use as fast in situ wood density assessment methods in this species. 相似文献8.
The dynamics of a fluid surface filled with high-amplitude ripples were studied with a technique (diffusing light photography) that resolves the height at all locations instantaneously. Even when nonlinearities are strong enough to generate a (Kolmogorov) cascade from long wavelength (where energy is input) to shorter wavelength, the resulting turbulent state contains large coherent spatial structures. The appearance of these structures in a thermal equilibrium state (with the same average energy) would be highly improbable. 相似文献
9.
TF. JUBB P. BRIGHTLING J. MALMO† MT. LARCOMBE GA. ANDERSON SJ. HIDES‡ 《Australian veterinary journal》1989,66(10):334-336
Anoestrous dairy cows in seasonally calving herds in the Macalister Irrigation District of Gippsland, Victoria were treated at the start of the mating period with a progesterone releasing intravaginal device (CIDR). The CIDR was inserted for 7 days and 400 IU of PMSG was injected intramuscularly at removal. There was no clinically useful difference among cows receiving the CIDR, a placebo and untreated cows in the interval from treatment to either first oestrus or conception, the conception rate to first service or percent pregnant by the end of mating. Analyses of data from 2-year-old cows, older cattle, cows calved at least 45 days or cows calved at least 55 days and cows treated 3 weeks after the start of mating did not show improved reproductive performance following treatment with the CIDR. 相似文献
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